New Lignans from the Leaves and Stems of Schisandra chinensis and Their Anti-HIV-1 Activities

CORC > 昆明动物研究所 > 昆明动物研究所 > 动物模型与人类重大疾病机理重点实验室 > 分子免疫药理学

	New Lignans from the Leaves and Stems of Schisandra chinensis and Their Anti-HIV-1 Activities
	Shi YM 1,3; Zhong WM 1,3; Chen H 2; Wang RR 2; Shang SZ 1,3; Liang CQ 1,3; Gao ZH 1,3; Zheng YT 2; Xiao WL[]1; Sun HD[]1
刊名	CHINESE JOURNAL OF CHEMISTRY
	2014
卷号	32 期号:8 页码:734-740
关键词	Schisandraceae Schisandra chinensis lignan anti-HIV-1
通讯作者	xwl@mail.kib.ac.cn ; hdsun@mail.kib.ac.cn
合作状况	其它
英文摘要	Six new lignans (1-6), as well as five known ones (7-11) were isolated from the leaves and stems of Schisandra chinensis. The structures of 1-6 were established on the basis of spectroscopic methods including 1D-and 2D-NMR techniques and CD experiments. Compound 1 was the first example of naturally occurring N-containing lignans featuring a nicotinoyl group. All the new compounds were evaluated for their anti-HIV-1 activities and showed EC50 values in the range 17.89-138.23 mu g/mL.
收录类别	SCI
资助信息	This project was supported financially by the Na- tional Natural Science Foundation of China (Nos. 81373290, 81102483), the Natural Science Foundation of Yunnan Province (No. 2012FB178), and the Chinese Academy of Sciences grant (No. KSCX2-EW-Q-10) and sponsored by the Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry to W.-L. Xiao.
语种	英语
WOS记录号	WOS:000341236900015
公开日期	2014-10-10
内容类型	期刊论文
源URL	[http://159.226.149.42:8088/handle/152453/8024]
专题	昆明动物研究所_分子免疫药理学昆明动物研究所_动物模型与人类重大疾病机理重点实验室
作者单位	1.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, Yunnan 650201, China 2.Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, China 3.University of Chinese Academy of Sciences, Beijing 100049, China
推荐引用方式 GB/T 7714	Shi YM,Zhong WM,Chen H,et al. New Lignans from the Leaves and Stems of Schisandra chinensis and Their Anti-HIV-1 Activities[J]. CHINESE JOURNAL OF CHEMISTRY,2014,32(8):734-740.
APA	Shi YM.,Zhong WM.,Chen H.,Wang RR.,Shang SZ.,...&Sun HD[*].(2014).New Lignans from the Leaves and Stems of Schisandra chinensis and Their Anti-HIV-1 Activities.CHINESE JOURNAL OF CHEMISTRY,32(8),734-740.
MLA	Shi YM,et al."New Lignans from the Leaves and Stems of Schisandra chinensis and Their Anti-HIV-1 Activities".CHINESE JOURNAL OF CHEMISTRY 32.8(2014):734-740.