Phenols with Anti-HIV Activity from Daphne acutiloba

CORC > 昆明动物研究所 > 昆明动物研究所 > 动物模型与人类重大疾病机理重点实验室 > 分子免疫药理学

	Phenols with Anti-HIV Activity from Daphne acutiloba
	Huang SZ 1,4; Zhang XJ 3,4; Li XY 3,4; Jiang HZ 1,4; Ma QY 2; Wang PC 1,4; Liu YQ 1; Hu JM 1; Zheng YT 3; Zhou J[*]1
刊名	PLANTA MEDICA
	2012
卷号	78 期号:2 页码:182-185
关键词	Daphne acutiloba Thymelaeceae anti-HIV activity phenols
通讯作者	jzhou@mail.kib.ac.cn ; zhaoyx1011@163.com
合作状况	其它
英文摘要	The present paper describes the study of the phytochemical properties and anti-HIV activity of the phenolic isolates of the plateau medicinal plant Daphne acutiloba Rehd. (Thymelaeceae). Two new lignans named daphnenin (1) and daphnetone (2), along with 11 known ones, were isolated, and their structures were elucidated by 1D and 2D NMR spectroscopy as well as HR-E-SI-MS. In the anti-HIV activity study, daphnenin (1) and caffeic acid n-octadecyl ester (13) showed definite anti-HIV activity with EC50 values of 0.39 and 0.16 mu g/mL, respectively.
收录类别	SCI
资助信息	This work was financially supported by the National Nonprofit Institute Research Grant of CATAS-ITBB (No.110301) and Natural Science Foundation of Yunnan (2008CD159).
语种	英语
WOS记录号	WOS:000299909300014
公开日期	2012-03-20
内容类型	期刊论文
源URL	[http://159.226.149.42:8088/handle/353002/6892]
专题	昆明动物研究所_分子免疫药理学
作者单位	1.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, Peopleʼs Republic of China 2.Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, Peopleʼs Republic of China 3.Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Peopleʼs Republic of China 4.Graduate School of the Chinese Academy of Sciences, Beijing, Peopleʼs Republic of China
推荐引用方式 GB/T 7714	Huang SZ,Zhang XJ,Li XY,et al. Phenols with Anti-HIV Activity from Daphne acutiloba[J]. PLANTA MEDICA,2012,78(2):182-185.
APA	Huang SZ.,Zhang XJ.,Li XY.,Jiang HZ.,Ma QY.,...&Zhao YX[*].(2012).Phenols with Anti-HIV Activity from Daphne acutiloba.PLANTA MEDICA,78(2),182-185.
MLA	Huang SZ,et al."Phenols with Anti-HIV Activity from Daphne acutiloba".PLANTA MEDICA 78.2(2012):182-185.