Anthraquinones and Lignans from Cassia occidentalis

CORC > 昆明动物研究所 > 昆明动物研究所 > 动物模型与人类重大疾病机理重点实验室 > 分子免疫药理学

	Anthraquinones and Lignans from Cassia occidentalis
	Li SF 1,2; Di YT 1; Wang YH 1; Tan CJ 1; Fang X 1; Zhang Y 1,2; Zheng YT 3; Li L 4; He HP 1; Li SL[*]1
刊名	HELVETICA CHIMICA ACTA
	2010
卷号	93 期号:9 页码:1795-1802
通讯作者	lisl@mail.kib.ac.cn ; haoxj@mail.kib.ac.cn
合作状况	其它
英文摘要	One new anthraquinone glycoside. 6-O-(alpha-L-rhamnopyranosyl (1 -> 6)-beta-D-glucopyranosyl)emodin (1). and two new sesquilignans. seslignanoccidentaliols A (2) and B (3), were isolated from the whole plant of Cassia occidentalis. The structures of the new compounds were established by means of spectroscopic methods, especially 2D-NMR data (H-1.H-1-COSY. HMQC, HMBC. and ROESY). as well as HR-ESI-MS analysis. One previously reported sesquilignan. crythro-guaiacylglycerol-beta-O-4'-(5')-methoxylariciresinol, was revised to be seslignanoccidentaliol A (2). The 6-O-(alpha-L-rhamnopyranosyl(1 -> 6)-beta-D-glucopyranosyl)emodin (1) exhibited moderate anti HIV-1 activity with an EC50 value of 2.90 mu g/ml and a therapeutic-index (TI) value of 260.
收录类别	SCI
资助信息	This work was supported by the National Natural Science Foundation of China (30760306) and the Yunnan Provincial Science Foundation (2006C009Z).
语种	英语
公开日期	2010-11-08
内容类型	期刊论文
源URL	[http://159.226.149.42:8088/handle/152453/6373]
专题	昆明动物研究所_分子免疫药理学
作者单位	1.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, P. R. China 2.Graduate School of Chinese Academy of Sciences, Beijing 100049, P. R. China 3.Laboratory of Molecular Immunopharmacology, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, P. R. China 4.Yunnan Pharmacological Laboratories of Natural Products, Kunming Medical College, Kunming 650031, P. R. China
推荐引用方式 GB/T 7714	Li SF,Di YT,Wang YH,et al. Anthraquinones and Lignans from Cassia occidentalis[J]. HELVETICA CHIMICA ACTA,2010,93(9):1795-1802.
APA	Li SF.,Di YT.,Wang YH.,Tan CJ.,Fang X.,...&Hao XJ[*].(2010).Anthraquinones and Lignans from Cassia occidentalis.HELVETICA CHIMICA ACTA,93(9),1795-1802.
MLA	Li SF,et al."Anthraquinones and Lignans from Cassia occidentalis".HELVETICA CHIMICA ACTA 93.9(2010):1795-1802.