Isatisine a, a novel alkaloid with an unprecedented skeleton from leaves of isatis indigotica | |
Liu JF1,2; Jiang ZY1; Wang RR3; Zheng YT3; Chen JJ[*]1,4; Zhang XM1; Ma YB1 | |
刊名 | ORGANIC LETTERS
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2007 | |
卷号 | 9期号:21页码:4172-4129 |
ISSN号 | 1523-7060 |
通讯作者 | chenjj@mai.kib.ac.cn |
合作状况 | 其它 |
英文摘要 | 9 alpha,13 alpha-Dihydroxylisopropylidenylisatisine A (1), which was derived from isatisine A (2) and possessed an unprecedented fused pentacyclic skeleton, was isolated from the leaves of Isatis indigotica Fort. The structure and relative configuration were elucidated on the basis of extensive NMR analyses and finally determined by single-crystal X-ray diffraction. Compound 1 showed moderate anti-HIV-1 activity with EC50 = 37.8 mu M and S1 = 7.98. |
收录类别 | 其他 |
原文出处 | 200794127.pdf |
语种 | 英语 |
公开日期 | 2010-08-24 |
内容类型 | 期刊论文 |
源URL | [http://159.226.149.42:8088/handle/152453/4577] ![]() |
专题 | 昆明动物研究所_分子免疫药理学 昆明动物研究所_动物模型与人类重大疾病机理重点实验室 |
作者单位 | 1.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, PRC 2.Graduate School of the Chinese Academy of Sciences. 3.Key Laboratory of Animal Models and Human Diseases Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223 4.The Joint-Laboratory of Anti-Viral Natural Medicines, Kunming Branch, Chinese Academy of Sciences, Graduate School of Chinese Academy of Sciences, Beijing 100039, PRC |
推荐引用方式 GB/T 7714 | Liu JF,Jiang ZY,Wang RR,et al. Isatisine a, a novel alkaloid with an unprecedented skeleton from leaves of isatis indigotica[J]. ORGANIC LETTERS,2007,9(21):4172-4129. |
APA | Liu JF.,Jiang ZY.,Wang RR.,Zheng YT.,Chen JJ[*].,...&Ma YB.(2007).Isatisine a, a novel alkaloid with an unprecedented skeleton from leaves of isatis indigotica.ORGANIC LETTERS,9(21),4172-4129. |
MLA | Liu JF,et al."Isatisine a, a novel alkaloid with an unprecedented skeleton from leaves of isatis indigotica".ORGANIC LETTERS 9.21(2007):4172-4129. |
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