Isatisine a, a novel alkaloid with an unprecedented skeleton from leaves of isatis indigotica
Liu JF1,2; Jiang ZY1; Wang RR3; Zheng YT3; Chen JJ[*]1,4; Zhang XM1; Ma YB1
刊名ORGANIC LETTERS
2007
卷号9期号:21页码:4172-4129
ISSN号1523-7060
通讯作者chenjj@mai.kib.ac.cn
合作状况其它
英文摘要9 alpha,13 alpha-Dihydroxylisopropylidenylisatisine A (1), which was derived from isatisine A (2) and possessed an unprecedented fused pentacyclic skeleton, was isolated from the leaves of Isatis indigotica Fort. The structure and relative configuration were elucidated on the basis of extensive NMR analyses and finally determined by single-crystal X-ray diffraction. Compound 1 showed moderate anti-HIV-1 activity with EC50 = 37.8 mu M and S1 = 7.98.
收录类别其他
原文出处200794127.pdf
语种英语
公开日期2010-08-24
内容类型期刊论文
源URL[http://159.226.149.42:8088/handle/152453/4577]  
专题昆明动物研究所_分子免疫药理学
昆明动物研究所_动物模型与人类重大疾病机理重点实验室
作者单位1.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, PRC
2.Graduate School of the Chinese Academy of Sciences.
3.Key Laboratory of Animal Models and Human Diseases Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223
4.The Joint-Laboratory of Anti-Viral Natural Medicines, Kunming Branch, Chinese Academy of Sciences, Graduate School of Chinese Academy of Sciences, Beijing 100039, PRC
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GB/T 7714
Liu JF,Jiang ZY,Wang RR,et al. Isatisine a, a novel alkaloid with an unprecedented skeleton from leaves of isatis indigotica[J]. ORGANIC LETTERS,2007,9(21):4172-4129.
APA Liu JF.,Jiang ZY.,Wang RR.,Zheng YT.,Chen JJ[*].,...&Ma YB.(2007).Isatisine a, a novel alkaloid with an unprecedented skeleton from leaves of isatis indigotica.ORGANIC LETTERS,9(21),4172-4129.
MLA Liu JF,et al."Isatisine a, a novel alkaloid with an unprecedented skeleton from leaves of isatis indigotica".ORGANIC LETTERS 9.21(2007):4172-4129.
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