Differential expression of the Brunol/CELF family genes during Xenopus laevis early development

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	Differential expression of the Brunol/CELF family genes during Xenopus laevis early development
	Wu JY 1,2; Li CC 1; Zhao SH 1,2; Mao BY[*]1
刊名	INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY
	2010
卷号	54 期号:1 页码:209-214
关键词	Brunol CELF Xenopus expression pattern
ISSN号	0214-6282
通讯作者	mao@mail.kiz.ac.cn
合作状况	其它
英文摘要	The BRUNOL/CELF family of RNA-binding proteins plays important roles in post-transcriptional regulation and has been implicated in several developmental processes. In this study, we describe the cloning and expression patterns of five Brunol genes in Xenopus laevis. Among them, only Brunol2 is maternally expressed and the zygotic expression of the other four Brunol genes starts at different developmental stages. During Xenopus development, Brunol1, 4-5 are exclusively expressed in the nervous system including domains in the brain, spinal cord, optic and otic vesicles. Brunol2 and 3 are expressed in both the somatic mesoderm and the nervous system. Brunol2 is also extensively expressed in the lens. In transfected Hela cells, BRUNOL1, 2 and 3 proteins are localized in both the cytoplasm and the nucleus, while BRUNOL4 and 5 are only present in the cytoplasm, indicating their different functions.
收录类别	SCI
资助信息	This work was supported by grants from the National Natural Science Foundation of China (30425011 and 305303800), the Key State Re- search Program from the Ministry of Science and Technology of China (2006CB943902 and 2007CB947201) and the Innovation Project of Chinese Academy of Sciences (KSCX2-YW-R-090).
语种	英语
公开日期	2010-08-24
内容类型	期刊论文
源URL	[http://159.226.149.42:8088/handle/152453/3175]
专题	昆明动物研究所_发育生物学昆明动物研究所_遗传资源与进化国家重点实验室
作者单位	1.CAS-Max Planck Junior Scientist Group, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China and 2.Graduate University of Chinese Academy of Sciences, Beijing, China
推荐引用方式 GB/T 7714	Wu JY,Li CC,Zhao SH,et al. Differential expression of the Brunol/CELF family genes during Xenopus laevis early development[J]. INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY,2010,54(1):209-214.
APA	Wu JY,Li CC,Zhao SH,&Mao BY[*].(2010).Differential expression of the Brunol/CELF family genes during Xenopus laevis early development.INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY,54(1),209-214.
MLA	Wu JY,et al."Differential expression of the Brunol/CELF family genes during Xenopus laevis early development".INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY 54.1(2010):209-214.