Cloning and developmental expression of the Xenopus Nkx6 genes

CORC > 昆明动物研究所 > 昆明动物研究所 > 遗传资源与进化国家重点实验室 > 发育生物学

	Cloning and developmental expression of the Xenopus Nkx6 genes
	Zhao SH 1,3; Jiang HF 2,3; Wang W 2; Mao BY[*]1,4
刊名	DEVELOPMENT GENES AND EVOLUTION
	2007
卷号	217 期号:6 页码:477-483
关键词	Nkx6 Xenopus Expressionpattern Centralnervoussystem Pancreas
ISSN号	0949-944X
通讯作者	mao@mail.kiz.ac.cn
合作状况	其它
英文摘要	The evolutionarily conserved Nkx6 family transcription factors play important roles in the patterning of the central nervous system (CNS) and pancreas in vertebrates. In this study, we describe the cloning and expression patterns of the three Nkx6 family genes in Xenopus laevis. Like their mouse and chicken homologues, Xenopus Nkx6 family genes are mainly expressed in the CNS and anterior endodermal tissues during embryonic development. Nkx6.1 and Nkx6.2 share overlapping expression domains in the ventral neural tube at neurula stages and later in the ventral part of developing hindbrain and spinal cord. Nkx6.3 is detected in the non-neural ectoderm from cleavage to early neurula stages and in the caudal hindbrain and the mandibular arch at tail bud stages. In the endoderm, Nkx6.2 is expressed in the hypochord at tail bud stages. At tadpole stages, the three Nkx6 genes are differentially expressed in the anterior endoderm derivatives, including the pancreas, stomach, esophagus, and lung.
收录类别	SCI
资助信息	This work was supported by grants from the National Natural Science Foundation of China, Grant numbers 30425011 and 30530380.
原文出处	2007217477.pdf
语种	英语
公开日期	2010-08-24
内容类型	期刊论文
源URL	[http://159.226.149.42:8088/handle/152453/3157]
专题	昆明动物研究所_发育生物学昆明动物研究所_基因起源组昆明动物研究所_细胞与分子进化重点实验室
作者单位	1.CAS-Max Planck Junior Scientist Group on Neural Patterning, Key Laboratory of Cellular and Molecular Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, People’s Republic of China 2.CAS-Max Planck Junior Scientist Group on Evolutionary Genomics, Key Laboratory of Cellular and Molecular Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, People’s Republic of China 3.Graduate University of Chinese Academy of Sciences, Beijing 100039, People’s Republic of China 4.Kunming Institute of Zoology, 32 East Jiao Chang Road, Kunming, Yunnan 650223, People’s Republic of China
推荐引用方式 GB/T 7714	Zhao SH,Jiang HF,Wang W,et al. Cloning and developmental expression of the Xenopus Nkx6 genes[J]. DEVELOPMENT GENES AND EVOLUTION,2007,217(6):477-483.
APA	Zhao SH,Jiang HF,Wang W,&Mao BY[*].(2007).Cloning and developmental expression of the Xenopus Nkx6 genes.DEVELOPMENT GENES AND EVOLUTION,217(6),477-483.
MLA	Zhao SH,et al."Cloning and developmental expression of the Xenopus Nkx6 genes".DEVELOPMENT GENES AND EVOLUTION 217.6(2007):477-483.