An Updated Phylogeny of the Human Y-Chromosome Lineage O2a-M95 with Novel SNPs

CORC > 昆明动物研究所 > 昆明动物研究所 > 遗传资源与进化国家重点实验室 > 比较基因组学

	An Updated Phylogeny of the Human Y-Chromosome Lineage O2a-M95 with Novel SNPs
	Zhang XM 1,6; Kampuansai J 2; Qi XB 1; Yan S 3; Yang ZH 1,6; Serey B 4; Sovannary T 4; Bunnath L 4; Aun HS 4; Samnom H 5
刊名	PLOS ONE
	2014
卷号	9 期号:6 页码:e101020
通讯作者	shihong@mail.kiz.ac.cn ; sub@mail.kiz.ac.cn
英文摘要	Though the Y-chromosome O2a-M95 lineage is one of the major haplogroups present in eastern Asian populations, especially among Austro-Asiatic speaking populations from Southwestern China and mainland Southeast Asia, to date its phylogeny lacks structure due to only one downstream SNP marker (M88) assigned to the lineage. A recent array-capture-based Y chromosome sequencing of Asian samples has yielded a variety of novel SNPs purportedly belonging to the O2a-M95 lineage, but their phylogenetic positions have yet to be determined. In this study, we sampled 646 unrelated males from 22 Austro-Asiatic speaking populations from Cambodia, Thailand and Southwestern China, and genotyped 12 SNP makers among the sampled populations, including 10 of the newly reported markers. Among the 646 males, 343 belonged to the O2a-M95 lineage, confirming the supposed dominance of this Y chromosome lineage in Austro-Asiatic speaking populations. We further characterized the phylogeny of O2a-M95 by defining 5 sub-branches: O2a1-M95, O2a1a-F789, O2a1b-F1252, O2a1b1*-M88 and O2a1b1a -F761. This updated phylogeny not only improves the resolution of this lineage, but also allows for greater tracing of the prehistory of human populations in eastern Asia and the Pacific, which may yield novel insights into the patterns of language diversification and population movement in these regions.
收录类别	SCI
资助信息	This study was supported by the National 973 Program of China (2012CB518202 to X.Q.), the National Natural Science Foundation of China (31130051 and 91231203 to B.S., 31371268 and 91131001 to H.S. and 31371269 to X.Q.) and the Natural Science Foundation of Yunnan Province (2010CI044 to H.S.)
语种	英语
WOS记录号	WOS:000338512200084
公开日期	2014-07-04
内容类型	期刊论文
源URL	[http://159.226.149.42:8088/handle/152453/7925]
专题	昆明动物研究所_比较基因组学昆明动物研究所_遗传资源与进化国家重点实验室
作者单位	1.State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China 2.Department of Biology, Faculty of Science, Chiang Mai University, Chiang Mai, Thailand 3.State Key Laboratory of Genetic Engineering and Ministry of Education, Key Laboratory of Contemporary Anthropology, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai, China 4.Department of Geography and Land Management, Royal University of Phnom Penh, Phnom Penh, Cambodia 5.Capacity Development Facilitator for Handicap International Federation and Freelance Research, Battambang, Cambodi 6.Kunming College of Life Science, University of Chinese Academy of Sciences, Beijing, China 7.Department of Biology, Faculty of Science, Khon Kaen University, Khon Kaen, Thailand
推荐引用方式 GB/T 7714	Zhang XM,Kampuansai J,Qi XB,et al. An Updated Phylogeny of the Human Y-Chromosome Lineage O2a-M95 with Novel SNPs[J]. PLOS ONE,2014,9(6):e101020.
APA	Zhang XM.,Kampuansai J.,Qi XB.,Yan S.,Yang ZH.,...&Su B[*].(2014).An Updated Phylogeny of the Human Y-Chromosome Lineage O2a-M95 with Novel SNPs.PLOS ONE,9(6),e101020.
MLA	Zhang XM,et al."An Updated Phylogeny of the Human Y-Chromosome Lineage O2a-M95 with Novel SNPs".PLOS ONE 9.6(2014):e101020.