Gold-Catalyzed Ring Expansion of Alkynyl Heterocycles through 1,2-Migration of an Endocyclic Carbon-Heteroatom Bond

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	Gold-Catalyzed Ring Expansion of Alkynyl Heterocycles through 1,2-Migration of an Endocyclic Carbon-Heteroatom Bond
	Chen M(陈铭); Sun N(孙宁); Xu W(徐炜); Zhao JD(赵继东); Wang GN(王高男); Liu YH(刘元红)
刊名	Chem.-Eur. J.
	2015
卷号	21 期号:51 页码:18571-18575
其他题名	通过1,2-杂原子迁移过程的金催化杂环-炔分子体系的氧化扩环反应
通讯作者	刘元红
英文摘要	A mild and efficient gold-catalyzed oxidative ring-expansion of a series of alkynyl heterocycles using pyridine-N-oxide as the oxidant has been developed, which affords highly valuable six- or seven-membered heterocycles with wide functional group toleration. The reaction consists of a regioselective oxidation and a chemoselective migration of an endocyclic carbon-heteroatom bond (favored over C-H migration) with the order of migratory aptitude for carbon-heteroatom bonds being C-S > C-N > C-O. In the absence of an oxidant, polycyclic products are readily constructed through a ring-expansion/Nazarov cyclization reaction sequence.
学科主题	金属有机化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1002/chem.201504165
语种	英语
WOS记录号	WOS:000368280400011
内容类型	期刊论文
源URL	[http://ir.sioc.ac.cn/handle/331003/39678]
专题	上海有机化学研究所_金属有机化学国家重点实验室
作者单位	中科院上海有机化学研究所, 金属有机化学国家重点实验室
推荐引用方式 GB/T 7714	Chen M,Sun N,Xu W,et al. Gold-Catalyzed Ring Expansion of Alkynyl Heterocycles through 1,2-Migration of an Endocyclic Carbon-Heteroatom Bond[J]. Chem.-Eur. J.,2015,21(51):18571-18575.
APA	陈铭,孙宁,徐炜,赵继东,王高男,&刘元红.(2015).Gold-Catalyzed Ring Expansion of Alkynyl Heterocycles through 1,2-Migration of an Endocyclic Carbon-Heteroatom Bond.Chem.-Eur. J.,21(51),18571-18575.
MLA	陈铭,et al."Gold-Catalyzed Ring Expansion of Alkynyl Heterocycles through 1,2-Migration of an Endocyclic Carbon-Heteroatom Bond".Chem.-Eur. J. 21.51(2015):18571-18575.