Diarylheptanoids of Curcuma comosa with Inhibitory Effects on Nitric Oxide Production in Macrophage RAW 264.7 Cells

	Diarylheptanoids of Curcuma comosa with Inhibitory Effects on Nitric Oxide Production in Macrophage RAW 264.7 Cells
	Sornkaew, Nilubon; Lin, Yuan; Wang, Fei; Zhang, Guolin; Chokchaisiri, Ratchanaporn; Zhang, Ailian; Wongkrajang, Kanjana; Suebsakwong, Parichat; Piyachaturawat, Pawinee; Suksamrarn, Apichart
刊名	NATURAL PRODUCT COMMUNICATIONS
	2015
卷号	10 期号:1 页码:89-93
关键词	ABSOLUTE-CONFIGURATION ALPINIA-OFFICINARUM CIRCULAR-DICHROISM AERIAL PARTS RHIZOMES PHYTOESTROGENS CONSTITUENTS
通讯作者	Suksamrarn, A (reprint author), Ramkhamhang Univ, Fac Sci, Dept Chem, Bangkok 10240, Thailand.
产权排序	2
合作状况	国际
英文摘要	Eight new diarylheptanoids, a 1.2:1 mixture of (3,S)- and (3R)-1-(4-hydroxyphenyl)-7-phenyl-(4E,6E)-4,6-heptadien-3-ol (1a and 1b), a racemic mixture of (35)- and (3R)-1-(4-hydroxyphenyl)-3-methoxy-7-phenyl-(4E,6E)-4,6-heptadiene (2a and 2b), a ca. 1:1 mixture of (3S)- and (3R)-1-(4-hydroxy-3methoxyphenyl)-3-methoxy-7-phenyl)-(4E,6E)-4,6-heptadiene (3a and 3b), 3-acetoxy-1-(3,4-dihydroxyphenyl)-7-phenylheptan-5-ol (4), (3R)-1-(4,5dihydroxyphenyl)-7-phenyl-(6E)-6-hepten-3,2'-epoxide (5), and thirteen known diarylheptanoids, 6-12, a 3:1 mixture of 13a and 13b, and 14-17, were isolated from the rhizomes of Curcuma comosa from Sakon Nakhon, northeastern part of Thailand. The isolated compounds were evaluated for their anti-inflammatory activities on the inhibition of lipopolysaccharide-induced nitric oxide production in macrophage RAW 264.7 cells and the diarylheptanoids la and 1b mixture and 14 exhibited potent inhibitory activity.
学科主题	Pharmacology & Pharmacy; Food Science & Technology
类目[WOS]	Chemistry, Medicinal ; Food Science & Technology
收录类别	SCI
语种	英语
内容类型	期刊论文
源URL	[http://210.75.237.14/handle/351003/27608]
专题	成都生物研究所_天然产物研究
推荐引用方式 GB/T 7714	Sornkaew, Nilubon,Lin, Yuan,Wang, Fei,et al. Diarylheptanoids of Curcuma comosa with Inhibitory Effects on Nitric Oxide Production in Macrophage RAW 264.7 Cells[J]. NATURAL PRODUCT COMMUNICATIONS,2015,10(1):89-93.
APA	Sornkaew, Nilubon.,Lin, Yuan.,Wang, Fei.,Zhang, Guolin.,Chokchaisiri, Ratchanaporn.,...&Suksamrarn, Apichart.(2015).Diarylheptanoids of Curcuma comosa with Inhibitory Effects on Nitric Oxide Production in Macrophage RAW 264.7 Cells.NATURAL PRODUCT COMMUNICATIONS,10(1),89-93.
MLA	Sornkaew, Nilubon,et al."Diarylheptanoids of Curcuma comosa with Inhibitory Effects on Nitric Oxide Production in Macrophage RAW 264.7 Cells".NATURAL PRODUCT COMMUNICATIONS 10.1(2015):89-93.