Analysis of the erythropoietin of a Tibetan Plateau schizothoracine fish (Gymnocypris dobula) reveals enhanced cytoprotection function in hypoxic environments

	Analysis of the erythropoietin of a Tibetan Plateau schizothoracine fish (Gymnocypris dobula) reveals enhanced cytoprotection function in hypoxic environments
	Xu, Qianghua 1,3; Zhang, Chi 1; Zhang, Dongsheng 2; Jiang, Huapeng 1; Peng, Sihua 2; Liu, Yang 1; Zhao, Kai 4; Wang, Congcong 1; Chen, Liangbiao 2
刊名	bmc evolutionary biology
	2016-01-15
卷号	16
关键词	EPO Qinghai-Tibet Plateau Schizothoracine fish Hypoxia adaptation Positive selection
英文摘要	background: erythropoietin (epo) is a glycoprotein hormone that plays a principal regulatory role in erythropoiesis and initiates cell homeostatic responses to environmental challenges. the qinghai-tibet plateau is a natural laboratory for hypoxia adaptation. gymnocypris dobula is a highly specialized plateau schizothoracine fish that is restricted to >4500 m high-altitude freshwater rivers and ponds in the qinghai-tibet plateau. the role of epo in the adaptation of schizothoracine fish to hypoxia is unknown.
WOS标题词	science & technology ; life sciences & biomedicine
类目[WOS]	evolutionary biology ; genetics & heredity
研究领域[WOS]	evolutionary biology ; genetics & heredity
关键词[WOS]	high-altitude adaptation ; zokor myospalax-baileyi ; mitochondrial genome ; ochotona-curzoniae ; cdna cloning ; expression ; proteins ; cells ; model ; gene
收录类别	SCI
语种	英语
WOS记录号	WOS:000368224500001
内容类型	期刊论文
源URL	[http://ir.nwipb.ac.cn/handle/363003/6503]
专题	西北高原生物研究所_中国科学院西北高原生物研究所
作者单位	1.Shanghai Ocean Univ, Coll Marine Sci, Key Lab Sustainable Exploitat Ocean Fisheries Res, Minist Educ, Shanghai, Peoples R China 2.Shanghai Ocean Univ, Coll Fisheries & Life Sci, Key Lab Aquaculture Resources & Utilizat, Minist Educ, Shanghai, Peoples R China 3.Collaborat Innovat Ctr Distant Water Fisheries, Shanghai, Peoples R China 4.Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Adaptat & Evolut Plateau Biota, Xining, Peoples R China
推荐引用方式 GB/T 7714	Xu, Qianghua,Zhang, Chi,Zhang, Dongsheng,et al. Analysis of the erythropoietin of a Tibetan Plateau schizothoracine fish (Gymnocypris dobula) reveals enhanced cytoprotection function in hypoxic environments[J]. bmc evolutionary biology,2016,16.
APA	Xu, Qianghua.,Zhang, Chi.,Zhang, Dongsheng.,Jiang, Huapeng.,Peng, Sihua.,...&Chen, Liangbiao.(2016).Analysis of the erythropoietin of a Tibetan Plateau schizothoracine fish (Gymnocypris dobula) reveals enhanced cytoprotection function in hypoxic environments.bmc evolutionary biology,16.
MLA	Xu, Qianghua,et al."Analysis of the erythropoietin of a Tibetan Plateau schizothoracine fish (Gymnocypris dobula) reveals enhanced cytoprotection function in hypoxic environments".bmc evolutionary biology 16(2016).