New sesquiterpenes and benzofuran derivatives from the aerial parts of Asterothamnus centrali-asiaticus

	New sesquiterpenes and benzofuran derivatives from the aerial parts of Asterothamnus centrali-asiaticus
	Wang, Yan-Ming 1,2,5; Zhao, Jian-Qiang 3,5; Zhou, Shuang-Yan 4; Yang, Jun-Li 1,2; Yao, Xiao-Jun 4; Tao, Yan-Duo 3; Mei, Li-Juan 3; Shi, Yan-Ping 1,2
刊名	tetrahedron
	2016-08-11
卷号	72 期号:32 页码:4910-4917
关键词	Asterothamnus centrali-asiaticus Sesquiterpenes Asterothamnones Benzofuran derivatives
英文摘要	phytochemical investigation on asterothamnus centrali-asiaticus afforded four new sesquiterpenes, asterothamnones a-d (1-4), and three new benzofuran derivatives (5-7) together with ten known compounds (8-17). their structures were elucidated using 1d and 2d nmr and x-ray diffraction analyses. compounds 1-4 were verified to be unusual eudesmane sesquiterpenes possessing 4,6-dien-3-one or 1,4,6-triene-3-one conjugated system. the absolute configurations of compounds 1-8 were established by means of calculated electronic circular dichroism (ecd). furthermore, all isolates were evaluated for their cytotoxic and anti-oxidant activities. results showed that 10, 12 and, 14 exhibited cytotoxic activity against hepg2 cancer cells and 14 displayed cytotoxicity against mgc-803 cancer cells. compounds 10 and 17 showed anti-oxidant effect. (c) 2016 elsevier ltd. all rights reserved.
WOS标题词	science & technology ; physical sciences
类目[WOS]	chemistry, organic
研究领域[WOS]	chemistry
关键词[WOS]	absolute-configuration ; chemical-constituents ; flowers ; glucosides
收录类别	SCI
语种	英语
WOS记录号	WOS:000380604100018
内容类型	期刊论文
源URL	[http://ir.nwipb.ac.cn/handle/363003/6462]
专题	西北高原生物研究所_中国科学院西北高原生物研究所
作者单位	1.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Chem Northwestern Plant Resources CAS, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Nat Med Gansu Prov, Lanzhou 730000, Peoples R China 3.Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Tibetan Med Res, Xining 810008, Peoples R China 4.Lanzhou Univ, Coll Chem & Chem Engn, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China 5.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Wang, Yan-Ming,Zhao, Jian-Qiang,Zhou, Shuang-Yan,et al. New sesquiterpenes and benzofuran derivatives from the aerial parts of Asterothamnus centrali-asiaticus[J]. tetrahedron,2016,72(32):4910-4917.
APA	Wang, Yan-Ming.,Zhao, Jian-Qiang.,Zhou, Shuang-Yan.,Yang, Jun-Li.,Yao, Xiao-Jun.,...&Shi, Yan-Ping.(2016).New sesquiterpenes and benzofuran derivatives from the aerial parts of Asterothamnus centrali-asiaticus.tetrahedron,72(32),4910-4917.
MLA	Wang, Yan-Ming,et al."New sesquiterpenes and benzofuran derivatives from the aerial parts of Asterothamnus centrali-asiaticus".tetrahedron 72.32(2016):4910-4917.