A new isocoumarin from the aerial parts of Aconitum gymnandrum

	A new isocoumarin from the aerial parts of Aconitum gymnandrum
	Zhao, Jian-Qiang 1,2,5; Wang, Yan-Ming 3,4,5; Wang, Shuo 1,2; Dang, Jun 1,2; Shi, Yan-Ping 3,4; Mei, Li-Juan 1,2; Tao, Yan-Duo 1,2
刊名	natural product research
	2016
卷号	30 期号:15 页码:1746-1752
关键词	Aconitum gymnandrum isocourmain cytotoxic activity
英文摘要	a new isocoumarin, along with 10 known compounds, was isolated from the aerial parts of aconitum gymnandrum. their structures were elucidated by spectroscopic methods including extensive 1d and 2d nmr techniques. among the known compounds, compound 11 was obtained as a natural product for the first time, which was previously reported as a synthetic product. in addition, compounds 1-5, 7 and 9 were tested for their cytotoxicity against four human cancer cell lines. the results showed that compounds 3, 4 and 7 displayed cytotoxicity against lung cancer a549 and gastric cancer mgc80, respectively, whereas 5 and 9 showed selective cytotoxicity against hepatocellular carcinoma hepg2.
WOS标题词	science & technology ; physical sciences ; life sciences & biomedicine
类目[WOS]	chemistry, applied ; chemistry, medicinal
研究领域[WOS]	chemistry ; pharmacology & pharmacy
关键词[WOS]	qinghai-tibetan plateau ; agrimonia-pilosa ; alkaloids
收录类别	SCI
语种	英语
WOS记录号	WOS:000382561200011
内容类型	期刊论文
源URL	[http://ir.nwipb.ac.cn/handle/363003/6433]
专题	西北高原生物研究所_中国科学院西北高原生物研究所
作者单位	1.Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Tibetan Med Res CAS, Xinning, Peoples R China 2.Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Tibetan Med Qinghai Prov, Xinning, Peoples R China 3.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Chem Northwestern Plant Resources CAS, Lanzhou, Peoples R China 4.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Nat Med Gansu Prov, Lanzhou, Peoples R China 5.Univ Chinese Acad Sci, Beijing, Peoples R China
推荐引用方式 GB/T 7714	Zhao, Jian-Qiang,Wang, Yan-Ming,Wang, Shuo,et al. A new isocoumarin from the aerial parts of Aconitum gymnandrum[J]. natural product research,2016,30(15):1746-1752.
APA	Zhao, Jian-Qiang.,Wang, Yan-Ming.,Wang, Shuo.,Dang, Jun.,Shi, Yan-Ping.,...&Tao, Yan-Duo.(2016).A new isocoumarin from the aerial parts of Aconitum gymnandrum.natural product research,30(15),1746-1752.
MLA	Zhao, Jian-Qiang,et al."A new isocoumarin from the aerial parts of Aconitum gymnandrum".natural product research 30.15(2016):1746-1752.