Preparation of photonic-magnetic responsive molecularly imprinted microspheres and their application to fast and selective extraction of 17β-estradiol

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 中科院海岸带环境过程与生态修复重点实验室

	Preparation of photonic-magnetic responsive molecularly imprinted microspheres and their application to fast and selective extraction of 17β-estradiol
	Peng, Hailong 1,2; Luo, Mei 1,2; Xiong, Hua 2; Yu, Ningxiang 2; Ning, Fangjian 2; Fan, Jieping 1; Zeng, Zheling 1; Li, Jinhua3 ; Chen, Lingxin3
刊名	Journal of Chromatography A
	2016
卷号	1442 页码:1-11
关键词	Nanomagnetics-Adsorption Bins Cost effectiveness Extraction Irradiation Magnetic separation Magnetism Microspheres Nanoparticles Potable water Separation Drinking water samples High adsorption capacity Magnetic nano-particles Molecularly imprinted microspheres Molecularly Imprinted Polymer Photo-responsive property Relative standard deviations Simultaneous separation
ISSN号	0021-9673
通讯作者	Xiong, Hua (huaxiong100@126.com)
产权排序	(1) School of Resources Environmental, Chemical Engineering, Nanchang University, Nanchang; 330031, China; (2) State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang; 330047, China; (3) Key Laboratory of Coastal Environmental Processes and Ecological Remediation, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai; 264003, China
英文摘要	Photonic-magnetic responsive molecularly imprinted microspheres (PM-MIMs) were prepared by seed polymerization, through suitable functionalization of magnetic nanoparticles for further coating with photoresponsive functional monomer and imprinted layers, and then were successfully applied to the fast and selective extraction of 17β-estradiol (17β-E2) from real samples. The PM-MIMs possessed a sandwich micro-spherical structure containing Fe3O4core, SiO2middle layer, and MIPs shell with thickness of 25 nm. The PM-MIMs displayed excellent photoresponsive properties and could be rapidly separated from solutions under an external magnet. The PM-MIMs had specific affinity towards 17β-E2with high adsorption capacity (Qmax = 0.84 mg g−1) and fast binding kinetics (Kd = 26.08 mg L−1). The PM-MIMs proved to be an ideal photoswitch with the ability of reversible uptake and release of 17β-E2upon alternate 365 and 440 nm irradiation: 45.0% of 17β-E2released from the PM-MIMs upon 365 nm irradiation, and 94.0% of the released 17β-E2was rebound to the PM-MIMs at 440 nm. Accordingly, the PM-MIMs were applied for fast separation and extraction of 17β-E2followed by HPLC-UV determination, presenting the low limit of detection (LOD, S/N = 3) and quantification (LOQ, S/N = 10) of 0.18 and 0.62 μmol L−1, respectively. The high recoveries for spiked milk powder and drinking water samples were in the range of 97.5–113.0% with relative standard deviations less than 4.4%. This study reasonably combined photonic response, magnetic separation and surface imprinting, which endowed the PM-MIMs with significant advantages of high adsorption capacity and fast binding kinetics, convenient separation and recycled use, and simple rapid eco-benign adsorption/elution processes for template molecules. Thus, the PM-MIMs based method may be a simple, rapid, convenient, cost-effective and environmentally-friendly way for simultaneous separation, enrichment and detection of trace 17β-E2in complicated matrices.
语种	英语
WOS记录号	WOS:35
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/17511]
专题	烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室
作者单位	1.School of Resources Environmental, Chemical Engineering, Nanchang University 2.State Key Laboratory of Food Science and Technology, Nanchang University 3.Key Laboratory of Coastal Environmental Processes and Ecological Remediation, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences
推荐引用方式 GB/T 7714	Peng, Hailong,Luo, Mei,Xiong, Hua,et al. Preparation of photonic-magnetic responsive molecularly imprinted microspheres and their application to fast and selective extraction of 17β-estradiol[J]. Journal of Chromatography A,2016,1442:1-11.
APA	Peng, Hailong.,Luo, Mei.,Xiong, Hua.,Yu, Ningxiang.,Ning, Fangjian.,...&Chen, Lingxin.(2016).Preparation of photonic-magnetic responsive molecularly imprinted microspheres and their application to fast and selective extraction of 17β-estradiol.Journal of Chromatography A,1442,1-11.
MLA	Peng, Hailong,et al."Preparation of photonic-magnetic responsive molecularly imprinted microspheres and their application to fast and selective extraction of 17β-estradiol".Journal of Chromatography A 1442(2016):1-11.