Citrinovirin with a new norditerpene skeleton from the marine algicolous fungus Trichoderma citrinoviride

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 海岸带生物学与生物资源利用重点实验室 > 海岸带生物学与生物资源利用所重点实验室

	Citrinovirin with a new norditerpene skeleton from the marine algicolous fungus Trichoderma citrinoviride
	Liang, XR; Miao, FP; Song, YP; Liu, XH; Ji, NY
刊名	BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
	2016-10-15
卷号	26 期号:20 页码:5029-5031
关键词	Marine algicolous fungi Trichoderma citrinoviride Norditerpene Citrinovirin
ISSN号	0960-894X
通讯作者	Ji, NY (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China. Email:nyji@yic.ac.cn
产权排序	[Liang, Xiao-Rui; Miao, Feng-Ping; Song, Yin-Ping; Liu, Xiang-Hong; Ji, Nai-Yun] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China; [Liang, Xiao-Rui] Naval Aeronaut & Astronaut Univ, Yantai 264001, Peoples R China; [Liang, Xiao-Rui; Song, Yin-Ping] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
英文摘要	Citrinovirin (1), a novel norditerpene with an unprecedented carbon skeleton along with three known compounds, cyclonerodiol (2), 3-(2-hydroxypropyl)-4-(hexa-2E, 4E-dien-6-yl)furan-2(5H)-one (3), and 5-hydroxy-3-hydroxymethyl-2-methyl-7-methoxychromone (4), was isolated from the culture of a marine brown alga-endophytic strain (cf-27) of Trichoderma citrinoviride. The structure and relative configuration of 1 were identified by spectroscopic methods, including 1D/2D NMR and MS. Its absolute configuration was established by analysis of ECD spectrum, aided by quantum chemical calculations. A plausible biogenetic pathway is proposed for 1, and it was evaluated to be active against Staphylococcus aureus. (C) 2016 Elsevier Ltd. All rights reserved.
研究领域[WOS]	Pharmacology & Pharmacy ; Chemistry
关键词[WOS]	PAECILOMYCES-VARIOTII ; NATURAL-PRODUCTS ; DITERPENES ; STRAIN
收录类别	SCI
语种	英语
WOS记录号	WOS:000385498500035
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/17462]
专题	烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室
推荐引用方式 GB/T 7714	Liang, XR,Miao, FP,Song, YP,et al. Citrinovirin with a new norditerpene skeleton from the marine algicolous fungus Trichoderma citrinoviride[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2016,26(20):5029-5031.
APA	Liang, XR,Miao, FP,Song, YP,Liu, XH,&Ji, NY.(2016).Citrinovirin with a new norditerpene skeleton from the marine algicolous fungus Trichoderma citrinoviride.BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,26(20),5029-5031.
MLA	Liang, XR,et al."Citrinovirin with a new norditerpene skeleton from the marine algicolous fungus Trichoderma citrinoviride".BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 26.20(2016):5029-5031.