Two new prenylated phenols from endogenous fungus Pestalotiopsis vaccinii of mangrove plant Kandelia candel (L.) Druce
Wang, Junfeng1; Wei, Xiaoyi1; Qin, Xiaochu1; Chen, Hao1; Lin, Xiuping1; Zhang, Tianyu1; Yang, Xianwen1; Liao, Shengrong1; Yang, Bin1; Liu, Juan1
刊名PHYTOCHEMISTRY LETTERS
2015
卷号12页码:59-62
关键词Pestalotiopsis vaccinii Structure elucidation COX-2 inhibitory activity
通讯作者yonghongliu@scsio.ac.cn
英文摘要Two new prenylated phenols vaccinol H (1) and vaccinol I (2), together with three known phenols derivatives 3-5, one glyceride derivative 6, and ergosterol 7 were isolated from endogenous Pestalotiopsis vaccinii (cgmcc3.9199) of mangrove plant Kandelia candel (L.) Druce (Rhizophoraceae). The new structures of 1 and 2 were determined by spectroscopic analyses and circular dichroism (CD) spectra. Most of the isolated compounds (2-6) were tested for their antiviral (EV71), cytotoxic, anti-tuberculosis, and anti-inflammatory effects. Among these compounds, compound 2 exhibited potent COX-2 inhibitory activity with an IC50 value of 16.8 mM. (C) 2015 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
学科主题Biochemistry & Molecular Biology; Plant Sciences
原文出处1874-3900
内容类型期刊论文
源URL[http://ir.scsio.ac.cn/handle/344004/14821]  
专题南海海洋研究所_中科院海洋生物资源可持续利用重点实验室
作者单位1.[Wang, Junfeng
2.Lin, Xiuping
3.Yang, Xianwen
4.Liao, Shengrong
5.Yang, Bin
6.Liu, Juan
7.Zhou, Xuefeng
8.Liu, Yonghong] Chinese Acad Sci, South China Sea Inst Oceanol, RNAM Ctr Marine Microbiol, CAS Key Lab Trop Marine Bioresources & Ecol,Guang, Guangzhou 510301, Guangdong, Peoples R China
9.[Wei, Xiaoyi] Chinese Acad Sci, Key Lab Plant Resources Conservat & Sustainable U, South China Bot Garden, Guangzhou 510650, Guangdong, Peoples R China
10.[Qin, Xiaochu
推荐引用方式
GB/T 7714
Wang, Junfeng,Wei, Xiaoyi,Qin, Xiaochu,et al. Two new prenylated phenols from endogenous fungus Pestalotiopsis vaccinii of mangrove plant Kandelia candel (L.) Druce[J]. PHYTOCHEMISTRY LETTERS,2015,12:59-62.
APA Wang, Junfeng.,Wei, Xiaoyi.,Qin, Xiaochu.,Chen, Hao.,Lin, Xiuping.,...&Liu, Yonghong.(2015).Two new prenylated phenols from endogenous fungus Pestalotiopsis vaccinii of mangrove plant Kandelia candel (L.) Druce.PHYTOCHEMISTRY LETTERS,12,59-62.
MLA Wang, Junfeng,et al."Two new prenylated phenols from endogenous fungus Pestalotiopsis vaccinii of mangrove plant Kandelia candel (L.) Druce".PHYTOCHEMISTRY LETTERS 12(2015):59-62.
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