Thermal and redox dual responsive poly(L-glutamate) with oligo(ethylene glycol) side-chains

	Thermal and redox dual responsive poly(L-glutamate) with oligo(ethylene glycol) side-chains
	Fu, Xiao-hui 1,2; Ma, Yi-nan 2; Sun, Jing 1; Li, Zhi-bo 1,2
刊名	CHINESE JOURNAL OF POLYMER SCIENCE
	2016-12-01
卷号	34 期号:12 页码:1436-1447
关键词	N-carboxyanhydride (NCA) Polypeptide Ring-opening polymerization Click chemistry Stimuli-responsive
英文摘要	A series of poly(L-glutamate)s grafted with oligo(ethylene glycol) (OEG) side-chains through the thioether linkages (PALG (n) -g-EG (x) , x = 2, 3 and 4) were prepared by ring-opening polymerization (ROP) of gamma-allyl-L-glutamate N-carboxyanhydride (ALG-NCA) and thiol-ene photoaddition. The chemical structures and physical properties were characterized by H-1-NMR, Fourier transform infrared (FTIR), circular dichroism (CD), etc. The PALG (n) -g-EG (x) samples with x = 3 and 4 displayed lower critical solution temperature (LCST) in water due to the presence of OEG units. The clouding point (CP) of polypeptides can be finely tuned by changing the side chain structures, molecular weights and sample concentrations. In addition, the thioether linkages in the side chains offer additional redox-responsive properties. The influence of both OEG units and thioether linkages on the LCST behavior was systematically investigated. This work provides an efficient way to prepare multi-stimuli responsive materials with highly tunable properties.
收录类别	SCI
语种	英语
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/35158]
专题	化学研究所_高分子物理与化学实验室
作者单位	1.Qingdao Univ Sci & Technol, Sch Polymer Sci & Engn, Qingdao 266042, Peoples R China 2.Chinese Acad Sci, Inst Chem, Lab Polymer Phys & Chem, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Fu, Xiao-hui,Ma, Yi-nan,Sun, Jing,et al. Thermal and redox dual responsive poly(L-glutamate) with oligo(ethylene glycol) side-chains[J]. CHINESE JOURNAL OF POLYMER SCIENCE,2016,34(12):1436-1447.
APA	Fu, Xiao-hui,Ma, Yi-nan,Sun, Jing,&Li, Zhi-bo.(2016).Thermal and redox dual responsive poly(L-glutamate) with oligo(ethylene glycol) side-chains.CHINESE JOURNAL OF POLYMER SCIENCE,34(12),1436-1447.
MLA	Fu, Xiao-hui,et al."Thermal and redox dual responsive poly(L-glutamate) with oligo(ethylene glycol) side-chains".CHINESE JOURNAL OF POLYMER SCIENCE 34.12(2016):1436-1447.