Synthesis of Tetrahydropyridine Derivatives through a Modular Assembly Reaction Using 3,4-Dihydropyran as Dual Substrate and Template
Sun, Shaohuan1; Cheng, Cheng1; Yang, Jian1; Taheri, Amir1; Jiang, Dan1; Zhang, Biao1; Gu YL(顾彦龙)1,2
刊名Organic Letters
2014
卷号16期号:17页码:4520-4523
ISSN号1523-7060
通讯作者顾彦龙
英文摘要A concise method to synthesize 1,2,3,4-tetrahydropyridines is described that involves the use of 2-alkoxy-3,4-dihydropyran as a modular precursor to react with aniline and a nucleophile. In this method, the heteroatom of the dihydropyran ring was replaced by nitrogen of aniline while the nucleophile attached to its adjacent position. Various druglike polyheterocycles were prepared with this method by using NH2-containing 1,5- or 1,4-bisnucleophiles.
学科主题物理化学与绿色催化
收录类别SCI
资助信息the National Natural Science Foundation of China (21173089;21373093);the Chutian Scholar Program of the Hubei Provincial Government and the Cooperative Innovation Center of Hubei Province;the fundamental research funds the central universities in China (2014ZZGH019)
语种英语
WOS记录号WOS:000341344600044
内容类型期刊论文
源URL[http://210.77.64.217/handle/362003/20336]  
专题兰州化学物理研究所_OSSO国家重点实验室
作者单位1.Huazhong Univ Sci & Technol, Sch Chem & Chem Engn, Minist Educ, Key Lab Large Format Battery Mat & Syst, Wuhan 430074, Peoples R China
2.Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China
推荐引用方式
GB/T 7714
Sun, Shaohuan,Cheng, Cheng,Yang, Jian,et al. Synthesis of Tetrahydropyridine Derivatives through a Modular Assembly Reaction Using 3,4-Dihydropyran as Dual Substrate and Template[J]. Organic Letters,2014,16(17):4520-4523.
APA Sun, Shaohuan.,Cheng, Cheng.,Yang, Jian.,Taheri, Amir.,Jiang, Dan.,...&Gu YL.(2014).Synthesis of Tetrahydropyridine Derivatives through a Modular Assembly Reaction Using 3,4-Dihydropyran as Dual Substrate and Template.Organic Letters,16(17),4520-4523.
MLA Sun, Shaohuan,et al."Synthesis of Tetrahydropyridine Derivatives through a Modular Assembly Reaction Using 3,4-Dihydropyran as Dual Substrate and Template".Organic Letters 16.17(2014):4520-4523.
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