Expedient Synthesis of Chiral alpha-Amino Acids through Nickel-Catalyzed Reductive Cross-Coupling

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	Expedient Synthesis of Chiral alpha-Amino Acids through Nickel-Catalyzed Reductive Cross-Coupling
	Lu, Xi 1,2,3; Yi, Jun 1; Zhang, Zhen-Qi 1; Dai, Jian-Jun 1; Liu, Jing-Hui 1; Xiao, Bin 1; Fu, Yao 1; Liu, Lei 1,2,3
刊名	Chemistry - A European Journal
	2014
卷号	20 期号:47 页码:15339-15343
关键词	amino acids catalysis C-C bond formation nickel reductive cross-coupling
ISSN号	0947-6539
通讯作者	Xiao, Bin ; Liu, Lei
英文摘要	A novel method for the synthesis of non-natural L- and D-amino acids by a Ni-catalyzed reductive cross-coupling reaction is described. This strategy enables the racemization-free cross-coupling of serine/homoserine-derived iodides with aryl/acyl/alkyl halides. It provides convenient access to varieties of enantiopure and functionalized amino acids, which are important building blocks in bioactive compounds and pharmaceuticals.
学科主题	物理化学与绿色催化
收录类别	SCI
资助信息	the "863" Program of the Ministry of Science and Technology (2012AA02A700);the National Basic Research Program of China (973 program, No. 2013CB932800);NSFC (Nos. 21472181;91313301;21221062);SRFDP (20133402120034)
语种	英语
WOS记录号	WOS:000345234800011
内容类型	期刊论文
源URL	[http://210.77.64.217/handle/362003/20286]
专题	兰州化学物理研究所_OSSO国家重点实验室
作者单位	1.Univ Sci & Technol China, Dept Chem, Hefei 230026, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China 3.Tsinghua Univ, Dept Chem, Beijing 100084, Peoples R China
推荐引用方式 GB/T 7714	Lu, Xi,Yi, Jun,Zhang, Zhen-Qi,et al. Expedient Synthesis of Chiral alpha-Amino Acids through Nickel-Catalyzed Reductive Cross-Coupling[J]. Chemistry - A European Journal,2014,20(47):15339-15343.
APA	Lu, Xi.,Yi, Jun.,Zhang, Zhen-Qi.,Dai, Jian-Jun.,Liu, Jing-Hui.,...&Liu, Lei.(2014).Expedient Synthesis of Chiral alpha-Amino Acids through Nickel-Catalyzed Reductive Cross-Coupling.Chemistry - A European Journal,20(47),15339-15343.
MLA	Lu, Xi,et al."Expedient Synthesis of Chiral alpha-Amino Acids through Nickel-Catalyzed Reductive Cross-Coupling".Chemistry - A European Journal 20.47(2014):15339-15343.