Bacillus sp strain P38: An efficient producer of L-lactate from cellulosic hydrolysate, with high tolerance for 2-furfural

	Bacillus sp strain P38: An efficient producer of L-lactate from cellulosic hydrolysate, with high tolerance for 2-furfural
	Peng, Lili 1,2; Wang, Limin 1; Che, Chengchuan 2; Yang, Ge 2; Yu, Bo 1; Ma, Yanhe 3
刊名	BIORESOURCE TECHNOLOGY
	2013-12-01
卷号	149 页码:169-176
关键词	L-Lactic acid Bacillus sp. 2-Furfural Cellulosic hydrolysate
英文摘要	In this study, efficient polymer-grade L-lactic acid production was achieved with the strain Bacillus sp. P38 by using cellulosic hydrolysate as the sole carbon source. In fed-batch fermentation, 180 g L-1 L-lactic acid was obtained with a volumetric productivity of 2.4 g L-1 h(-1) and a yield of 0.96 g g(-1) total reducing sugars. No D-isomer of lactic acid was detected in the broth. Strain P38 tolerated up to 10 g L-1 2-furfural, and lactate production was sharply inhibited only when the 2-furfural concentration was higher than 6 g L-1. Moreover, strain P38 also tolerated high concentrations (>6 g L-1) of other fermentation inhibitors in cellulosic hydrolysate, such as vanillin and acetic acid, although it was slightly sensitive to formic acid. The efficient L-lactic acid production, combined with high inhibitor tolerance and efficient pentose utilization, indicate that Bacillus sp. P38 is a promising producer of polymer-grade L-lactic acid from cellulosic biomass. (C) 2013 Elsevier Ltd. All rights reserved.
WOS标题词	Science & Technology ; Life Sciences & Biomedicine ; Technology
类目[WOS]	Agricultural Engineering ; Biotechnology & Applied Microbiology ; Energy & Fuels
研究领域[WOS]	Agriculture ; Biotechnology & Applied Microbiology ; Energy & Fuels
关键词[WOS]	LACTIC-ACID PRODUCTION ; L(+)-LACTIC ACID ; FERMENTATION ; COAGULANS ; BIOMASS ; XYLOSE ; INHIBITION ; MECHANISMS ; BACTERIA ; SUGARS
收录类别	SCI
语种	英语
WOS记录号	WOS:000328525300024
内容类型	期刊论文
源URL	[http://124.16.173.210/handle/834782/1229]
专题	天津工业生物技术研究所_酶工程实验室马延和 _期刊论文
作者单位	1.Chinese Acad Sci, Inst Microbiol, CAS Key Lab Microbial Physiol & Metab Engn, Beijing 100101, Peoples R China 2.Qufu Normal Univ, Coll Life Sci, Qufu 273165, Peoples R China 3.Chinese Acad Sci, Tianjin Inst Ind Biotechnol, Tianjin 300308, Peoples R China
推荐引用方式 GB/T 7714	Peng, Lili,Wang, Limin,Che, Chengchuan,et al. Bacillus sp strain P38: An efficient producer of L-lactate from cellulosic hydrolysate, with high tolerance for 2-furfural[J]. BIORESOURCE TECHNOLOGY,2013,149:169-176.
APA	Peng, Lili,Wang, Limin,Che, Chengchuan,Yang, Ge,Yu, Bo,&Ma, Yanhe.(2013).Bacillus sp strain P38: An efficient producer of L-lactate from cellulosic hydrolysate, with high tolerance for 2-furfural.BIORESOURCE TECHNOLOGY,149,169-176.
MLA	Peng, Lili,et al."Bacillus sp strain P38: An efficient producer of L-lactate from cellulosic hydrolysate, with high tolerance for 2-furfural".BIORESOURCE TECHNOLOGY 149(2013):169-176.