Inverse associations of outdoor activity and vitamin D intake with the risk of Parkinson's disease

	Inverse associations of outdoor activity and vitamin D intake with the risk of Parkinson's disease
	Zhu, Dan 1; Liu, Gui-you 2; Lv, Zheng 3; Wen, Shi-rong 4; Bi, Sheng 4; Wang, Wei-zhi 1
刊名	JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B
	2014-10-01
卷号	15 期号:10 页码:923-927
关键词	Outdoor activity Vitamin D intake Parkinson's disease
英文摘要	Early studies had suggested that vitamin D intake was inversely associated with neurodegenerative diseases, such as Alzheimer's disease and multiple sclerosis. However, the associations of vitamin D intake and outdoor activities with Parkinson's disease (PD) are still unclear, so this study is to evaluate these relationships from a case-control study in elderly Chinese. The study population involved 209 cases with new onsets of PD and 210 controls without neurodegenerative diseases. The data on dietary vitamin D and outdoor activities were collected using a food-frequency questionnaire and self-report questionnaire. Multivariable logistic regressions were used to examine the associations between dietary outdoor activities, vitamin D intake and PD. Adjustment was made for sex, age, smoking, alcohol use, education, and body mass index (BMI). Adjusted odds ratios (ORs) for PD in quartiles for outdoor physical activity were 1 (reference), 0.739 (0.413, 1.321), 0.501 (0.282, 0.891), and 0.437 (0.241, 0.795), respectively (P=0.002 for trend). Adjusted ORs for PD in quartiles for total vitamin D intake were 1 (reference), 0.647 (0.357, 1.170), 0.571 (0.318, 1.022), and 0.538 (0.301, 0.960), respectively (P=0.011 for trend). Our study suggested that outdoor activity and total vitamin D intake were inversely associated with PD, and outdoor activity seems to be more significantly associated with decreased risk for PD.
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
类目[WOS]	Biochemistry & Molecular Biology ; Biotechnology & Applied Microbiology ; Medicine, Research & Experimental
研究领域[WOS]	Biochemistry & Molecular Biology ; Biotechnology & Applied Microbiology ; Research & Experimental Medicine
关键词[WOS]	PHYSICAL-ACTIVITY ; FUTURE RISK ; SUPPLEMENTATION ; METAANALYSIS ; GUIDELINES ; FOODS
收录类别	SCI
语种	英语
WOS记录号	WOS:000343904100009
内容类型	期刊论文
源URL	[http://124.16.173.210/handle/834782/1404]
专题	天津工业生物技术研究所_基因组分析实验室陈祖耕_期刊论文
作者单位	1.Harbin Med Univ, Affiliated Hosp 2, Dept Neurol, Harbin 150086, Peoples R China 2.Chinese Acad Sci, Tianjin Inst Ind Biotechnol, Genome Anal Lab, Tianjin 300308, Peoples R China 3.Harbin Med Univ, Affiliated Hosp 1, Dept Rehabil, Harbin 150001, Peoples R China 4.Harbin Med Univ, Affiliated Hosp 1, Dept Neurol, Harbin 150001, Peoples R China
推荐引用方式 GB/T 7714	Zhu, Dan,Liu, Gui-you,Lv, Zheng,et al. Inverse associations of outdoor activity and vitamin D intake with the risk of Parkinson's disease[J]. JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B,2014,15(10):923-927.
APA	Zhu, Dan,Liu, Gui-you,Lv, Zheng,Wen, Shi-rong,Bi, Sheng,&Wang, Wei-zhi.(2014).Inverse associations of outdoor activity and vitamin D intake with the risk of Parkinson's disease.JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B,15(10),923-927.
MLA	Zhu, Dan,et al."Inverse associations of outdoor activity and vitamin D intake with the risk of Parkinson's disease".JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B 15.10(2014):923-927.