Cytotoxic Meroterpenoids with Rare Skeletons from Psidium guajava Cultivated in Temperate Zone

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Cytotoxic Meroterpenoids with Rare Skeletons from Psidium guajava Cultivated in Temperate Zone
	Qin, Xu-Jie; Yan, Huan; Ni, Wei; Yu, Mu-Yuan; Khan, Afsar; Liu, Hui; Zhang, Hong-Xia; He, Li; Hao, Xiao-Jiang; Di, Ying-Tong
刊名	SCIENTIFIC REPORTS
	2016-09-02
卷号	6
英文摘要	Three new meroterpenoids, guajavadials A-C (1-3), were isolated from Psidium guajava cultivated in temperate zone. Their structures were established by extensive spectroscopic evidence and electronic circular dichroism (ECD) calculations. Guajavadial A (1) represents a novel skeleton of the 3,5-diformylbenzyl phloroglucinol-coupled monoterpenoid, while guajavadials B (2) and C (3) are new adducts of the 3,5-diformylbenzyl phloroglucinol and a sesquiterpene with different coupling models. The plausible biosynthetic pathways as well as antimicrobial and cytotoxic activities of these meroterpenoids are also discussed. All these isolates exhibited moderate cytotoxicities against five human cancer cell lines, with 3 being most effective with an IC50 value of 3.54 mu M toward SMMC-7721 cell lines.
类目[WOS]	Multidisciplinary Sciences
研究领域[WOS]	Science & Technology - Other Topics
关键词[WOS]	LEAVES
收录类别	SCI
语种	英语
WOS记录号	WOS:000382397500001
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/28597]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
推荐引用方式 GB/T 7714	Qin, Xu-Jie,Yan, Huan,Ni, Wei,et al. Cytotoxic Meroterpenoids with Rare Skeletons from Psidium guajava Cultivated in Temperate Zone[J]. SCIENTIFIC REPORTS,2016,6.
APA	Qin, Xu-Jie.,Yan, Huan.,Ni, Wei.,Yu, Mu-Yuan.,Khan, Afsar.,...&Liu, Hai-Yang.(2016).Cytotoxic Meroterpenoids with Rare Skeletons from Psidium guajava Cultivated in Temperate Zone.SCIENTIFIC REPORTS,6.
MLA	Qin, Xu-Jie,et al."Cytotoxic Meroterpenoids with Rare Skeletons from Psidium guajava Cultivated in Temperate Zone".SCIENTIFIC REPORTS 6(2016).