Cytotoxic Meroterpenoids with Rare Skeletons from Psidium guajava Cultivated in Temperate Zone | |
Qin, Xu-Jie![]() ![]() ![]() ![]() ![]() | |
刊名 | SCIENTIFIC REPORTS
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2016-09-02 | |
卷号 | 6 |
英文摘要 | Three new meroterpenoids, guajavadials A-C (1-3), were isolated from Psidium guajava cultivated in temperate zone. Their structures were established by extensive spectroscopic evidence and electronic circular dichroism (ECD) calculations. Guajavadial A (1) represents a novel skeleton of the 3,5-diformylbenzyl phloroglucinol-coupled monoterpenoid, while guajavadials B (2) and C (3) are new adducts of the 3,5-diformylbenzyl phloroglucinol and a sesquiterpene with different coupling models. The plausible biosynthetic pathways as well as antimicrobial and cytotoxic activities of these meroterpenoids are also discussed. All these isolates exhibited moderate cytotoxicities against five human cancer cell lines, with 3 being most effective with an IC50 value of 3.54 mu M toward SMMC-7721 cell lines. |
类目[WOS] | Multidisciplinary Sciences |
研究领域[WOS] | Science & Technology - Other Topics |
关键词[WOS] | LEAVES |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000382397500001 |
内容类型 | 期刊论文 |
源URL | [http://ir.kib.ac.cn/handle/151853/28597] ![]() |
专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
推荐引用方式 GB/T 7714 | Qin, Xu-Jie,Yan, Huan,Ni, Wei,et al. Cytotoxic Meroterpenoids with Rare Skeletons from Psidium guajava Cultivated in Temperate Zone[J]. SCIENTIFIC REPORTS,2016,6. |
APA | Qin, Xu-Jie.,Yan, Huan.,Ni, Wei.,Yu, Mu-Yuan.,Khan, Afsar.,...&Liu, Hai-Yang.(2016).Cytotoxic Meroterpenoids with Rare Skeletons from Psidium guajava Cultivated in Temperate Zone.SCIENTIFIC REPORTS,6. |
MLA | Qin, Xu-Jie,et al."Cytotoxic Meroterpenoids with Rare Skeletons from Psidium guajava Cultivated in Temperate Zone".SCIENTIFIC REPORTS 6(2016). |
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