Palladium-Catalyzed C(sp(3))-H Functionalization at the C3 Position of L-Pipecolinic Acid Derivatives

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Palladium-Catalyzed C(sp(3))-H Functionalization at the C3 Position of L-Pipecolinic Acid Derivatives
	Yu, Qun-Ying 1,2; Zhong, Hong-Ming 1,2; Sun, Wen-Wu1,2 ; Zhang, Shi-Jin 1,4; Cao, Pei 1; Dong, Xiao-Ping 4; Qin, Hong-Bo1 ; Liu, Ji-Kai 3; Wu, Bin 1,3
刊名	ASIAN JOURNAL OF ORGANIC CHEMISTRY
	2016-05-01
卷号	5 期号:5 页码:608-612
关键词	alkoxylation arylation C-H activation palladium pipecolinic acid
英文摘要	The study of Pd-catalyzed arylation, alkoxylation, and acyloxylation reactions at the C3 position of L-pipecolinic acid derivatives to afford cis-disubstituted piperidines as single stereoisomers was performed. To demonstrate the utility of the reaction, compound 10, an analogue of (-)-3S-3-PPP (9) that is used as a neuroleptic drug for the treatment of schizophrenia, was synthesized featuring the arylation and radical decarboxylation reactions as key steps.
类目[WOS]	Chemistry, Organic
研究领域[WOS]	Chemistry
关键词[WOS]	DOPAMINE AUTORECEPTOR ANTAGONISTS ; CARBON-HYDROGEN BONDS ; UNACTIVATED C(SP(3))-H ; STEREOSELECTIVE-SYNTHESIS ; H BONDS ; BETA-LACTAMS ; INTRAMOLECULAR AMINATION ; PIPERIDINE ALKALOIDS ; ASYMMETRIC-SYNTHESIS ; COUPLING REACTIONS
收录类别	SCI
语种	英语
WOS记录号	WOS:000380259700002
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/28511]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, 132 Lanhei Rd, Kunming 650201, Yunnan, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.South Cent Univ Nationalities, Sch Pharmaceut Sci, Wuhan 430074, Peoples R China 4.Chengdu Univ Tradit Chinese Med, Coll Pharm, Chengdu 611137, Peoples R China
推荐引用方式 GB/T 7714	Yu, Qun-Ying,Zhong, Hong-Ming,Sun, Wen-Wu,et al. Palladium-Catalyzed C(sp(3))-H Functionalization at the C3 Position of L-Pipecolinic Acid Derivatives[J]. ASIAN JOURNAL OF ORGANIC CHEMISTRY,2016,5(5):608-612.
APA	Yu, Qun-Ying.,Zhong, Hong-Ming.,Sun, Wen-Wu.,Zhang, Shi-Jin.,Cao, Pei.,...&Wu, Bin.(2016).Palladium-Catalyzed C(sp(3))-H Functionalization at the C3 Position of L-Pipecolinic Acid Derivatives.ASIAN JOURNAL OF ORGANIC CHEMISTRY,5(5),608-612.
MLA	Yu, Qun-Ying,et al."Palladium-Catalyzed C(sp(3))-H Functionalization at the C3 Position of L-Pipecolinic Acid Derivatives".ASIAN JOURNAL OF ORGANIC CHEMISTRY 5.5(2016):608-612.