Three New Pregnane Alkaloids from Pachysandra terminalis

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Three New Pregnane Alkaloids from Pachysandra terminalis
	Sun, Yun; Chen, Jin-Xiong; Chen, Jian-Chao; Li, Zhong-Rong; Zhou, Lin; Li, Yan; Qiu, Ming-Hua
刊名	HELVETICA CHIMICA ACTA
	2016-07-01
卷号	99 期号:7 页码:513-517
关键词	Pregnane alkaloids Buxaceae Pachysandra terminalis Cytotoxicity
英文摘要	Three new pregnane alkaloids, pachystermine C (1), pachysanamine A (2), and pachysanamine B (3), together with four known ones, pachystermine B (4), pachysamine A (5), (20S)-20-(dimethylamino)-16-hydroxy-3-(3-isopropyl)lactam-5-pregnan-4-one (6), and E-salignone (7), were isolated from Pachysandra terminalis. The chemical structures of the new alkaloids were elucidated by spectroscopic methods. All the compounds were evaluated for their inhibitory activities against HL-60, SMMC-7721, A-549, MCF-7, and SW480 cell lines, some of the compounds showed stronger cytotoxicity for the test cell lines, especially compounds 2, 3, and 7.
类目[WOS]	Chemistry, Multidisciplinary
研究领域[WOS]	Chemistry
关键词[WOS]	STEROIDAL ALKALOIDS ; ZUCC ; SIEB ; AXILLARIS
收录类别	SCI
语种	英语
WOS记录号	WOS:000379937300005
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/28488]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
推荐引用方式 GB/T 7714	Sun, Yun,Chen, Jin-Xiong,Chen, Jian-Chao,et al. Three New Pregnane Alkaloids from Pachysandra terminalis[J]. HELVETICA CHIMICA ACTA,2016,99(7):513-517.
APA	Sun, Yun.,Chen, Jin-Xiong.,Chen, Jian-Chao.,Li, Zhong-Rong.,Zhou, Lin.,...&Qiu, Ming-Hua.(2016).Three New Pregnane Alkaloids from Pachysandra terminalis.HELVETICA CHIMICA ACTA,99(7),513-517.
MLA	Sun, Yun,et al."Three New Pregnane Alkaloids from Pachysandra terminalis".HELVETICA CHIMICA ACTA 99.7(2016):513-517.