Vibsane-type diterpenes from leaves and twigs of Viburnum odoratissimum
He, Juan1; Peng, Li-Yan1; Tu, Lin1; Wu, Xing-De1; Dong, Liao-Bing1; Pan, Zheng-Hong2; Chen, Xuan-Qin3; Su, Jia1; Zhao, Yu1; Xu, Gang1
刊名FITOTERAPIA
2016-03-01
卷号109页码:224-229
关键词Viburnum odoratissimum Vibsane-type diterpenes Vibsanols C-H Vibsanin X Cytotoxicity
英文摘要Seven new vibsane-type diterpenes, vibsanols C-H (1-6) and vibsanin X (7), together with seven analogues, were isolated from the leaves and twigs of Viburnum odoratissimum. The structures of the new compounds were 'elucidated by extensive spectroscopic methods. All the new compounds were detected for their cytotoxicity. Compound 1 showed significant cytotoxicity against all the tested cell lines (HL-60, SMMC-7721, A-594, MCF7, and SW-480), with IC50 values of 3.35, 4.41, 5.18,1130, and 3.70 M, respectively. Compounds 4 and 5 also displayed significant cytotoxicity against hepatocellular carcinoma SMMC-7721 cell line, with IC50 values of 3.69 and 3.52 M, respectively. (C) 2016 Elsevier B.V. All rights reserved.
类目[WOS]Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]Pharmacology & Pharmacy
关键词[WOS]AWABUKI ; DERIVATIVES
收录类别SCI
语种英语
WOS记录号WOS:000372685400036
内容类型期刊论文
源URL[http://ir.kib.ac.cn/handle/151853/26193]  
专题昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Guangxi Inst Bot, Guilin 541006, Peoples R China
3.Kunming Univ Sci & Technol, Kunming 650093, Peoples R China
推荐引用方式
GB/T 7714
He, Juan,Peng, Li-Yan,Tu, Lin,et al. Vibsane-type diterpenes from leaves and twigs of Viburnum odoratissimum[J]. FITOTERAPIA,2016,109:224-229.
APA He, Juan.,Peng, Li-Yan.,Tu, Lin.,Wu, Xing-De.,Dong, Liao-Bing.,...&Zhao, Qin-Shi.(2016).Vibsane-type diterpenes from leaves and twigs of Viburnum odoratissimum.FITOTERAPIA,109,224-229.
MLA He, Juan,et al."Vibsane-type diterpenes from leaves and twigs of Viburnum odoratissimum".FITOTERAPIA 109(2016):224-229.
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