Cytotoxic limonoids from the leaves of Walsura robusta

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Cytotoxic limonoids from the leaves of Walsura robusta
	Ji, Kai-Long 1,2; Li, Xiao-Nian 3; Liao, Shang-Gao 4,5; Hu, Hua-Bin 1; Li, Ren 1; Xu, You-Kai 1
刊名	PHYTOCHEMISTRY LETTERS
	2016-03-01
卷号	15 页码:53-56
关键词	Walsura robusta Meliaceae Limonoids Cytotoxicity
英文摘要	Two new vilasinin limonoids, walsuronoids D-E (1-2), along with three known compounds (3-5) were isolated and identified from the leaves of Walsura robusta. Their structures were established based on extensive spectroscopic analysis. Compounds 1-2 showed potent cytotoxic activity against HL-60, SMMC-7721, A-549, MCF-7, and SW480 cancer cell lines, with IC50 values ranging from 2.7 to 4.5 mu M. The absolute configuration of 3 was determined to be (24R, 25S)-cycloartane-3 beta,24,25,26-tetrol for the first time by using X-ray diffraction analysis. (C) 2015 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
类目[WOS]	Biochemistry & Molecular Biology ; Plant Sciences
研究领域[WOS]	Biochemistry & Molecular Biology ; Plant Sciences
关键词[WOS]	COCHINCHINENSIS ; YUNNANENSIS
收录类别	SCI
语种	英语
WOS记录号	WOS:000371798400011
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/26011]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Key Lab Trop Plant Resources & Sustainable Use, Xishuangbanna Trop Bot Garden, Menglun 666303, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources West Ch, Kunming Inst Bot, Kunming 650201, Peoples R China 4.Guiyang Med Coll, Sch Pharm, Guiyang 550004, Peoples R China 5.Minist Educ, Engn Res Ctr Dev & Applicat Ethn Med & TCM, Guiyang 550004, Peoples R China
推荐引用方式 GB/T 7714	Ji, Kai-Long,Li, Xiao-Nian,Liao, Shang-Gao,et al. Cytotoxic limonoids from the leaves of Walsura robusta[J]. PHYTOCHEMISTRY LETTERS,2016,15:53-56.
APA	Ji, Kai-Long,Li, Xiao-Nian,Liao, Shang-Gao,Hu, Hua-Bin,Li, Ren,&Xu, You-Kai.(2016).Cytotoxic limonoids from the leaves of Walsura robusta.PHYTOCHEMISTRY LETTERS,15,53-56.
MLA	Ji, Kai-Long,et al."Cytotoxic limonoids from the leaves of Walsura robusta".PHYTOCHEMISTRY LETTERS 15(2016):53-56.