Right-handed and left-handed G-quadruplexes have the same DNA sequence: distinct conformations induced by an organic small molecule and potassium

CORC > 武汉物理与数学研究所 > 中国科学院武汉物理与数学研究所 > 磁共振应用研究部

	Right-handed and left-handed G-quadruplexes have the same DNA sequence: distinct conformations induced by an organic small molecule and potassium
	Fu, Boshi 1; Huang, Jinguo 1; Chen, Yuqi 1; Wang, Yafen 1; Xue, Tianrui 1; Xu, GuoHua 2; Wang, Shaoru 1; Zhou, Xiang 1
刊名	CHEMICAL COMMUNICATIONS
	2016
卷号	52 期号:65 页码:10052-10055
英文摘要	Herein, we report two distinct G-quadruplex conformations of the same G-rich oligonucleotide, regulated by a small molecule. This is the first report in which both right-and left-handed G-quadruplex conformations have been obtained from the same sequence. We discriminated these two distinct conformations and investigated their kinetics and thermodynamics.
WOS标题词	Science & Technology ; Physical Sciences
类目[WOS]	Chemistry, Multidisciplinary
研究领域[WOS]	Chemistry
关键词[WOS]	TELOMERE G-QUADRUPLEX ; DRUG DESIGN ; PEROXIDASE-ACTIVITY ; CIRCULAR-DICHROISM ; CRYSTAL-STRUCTURE ; PROMOTER REGION ; NUCLEIC-ACIDS ; DOUBLE HELIX ; STABILITY ; TOPOLOGY
收录类别	SCI
语种	英语
WOS记录号	WOS:000381437300017
内容类型	期刊论文
源URL	[http://ir.wipm.ac.cn/handle/112942/9501]
专题	武汉物理与数学研究所_磁共振应用研究部
作者单位	1.Wuhan Univ, Coll Chem & Mol Sci, Inst Adv Studies, Key Lab Biomed Polymers,Minist Educ, Wuhan 430072, Hubei, Peoples R China 2.Chinese Acad Sci, Wuhan Inst Phys & Math, Wuhan 430071, Hubei, Peoples R China
推荐引用方式 GB/T 7714	Fu, Boshi,Huang, Jinguo,Chen, Yuqi,et al. Right-handed and left-handed G-quadruplexes have the same DNA sequence: distinct conformations induced by an organic small molecule and potassium[J]. CHEMICAL COMMUNICATIONS,2016,52(65):10052-10055.
APA	Fu, Boshi.,Huang, Jinguo.,Chen, Yuqi.,Wang, Yafen.,Xue, Tianrui.,...&Zhou, Xiang.(2016).Right-handed and left-handed G-quadruplexes have the same DNA sequence: distinct conformations induced by an organic small molecule and potassium.CHEMICAL COMMUNICATIONS,52(65),10052-10055.
MLA	Fu, Boshi,et al."Right-handed and left-handed G-quadruplexes have the same DNA sequence: distinct conformations induced by an organic small molecule and potassium".CHEMICAL COMMUNICATIONS 52.65(2016):10052-10055.