Enantioselective Pd-Catalyzed Allylation of Acyclic alpha-Fluorinated Ketones

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	Enantioselective Pd-Catalyzed Allylation of Acyclic alpha-Fluorinated Ketones
	Wang WG(王文贵); Shen HM(沈海明); Wan XL(万晓龙); Chen QY(陈庆云); Guo Y(郭勇)
刊名	J. Org. Chem.
	2014
卷号	79 期号:13 页码:6347-6353
其他题名	链状α?氟代酮的不对称钯催化烯丙基化反应
通讯作者	陈庆云 ; 郭勇
英文摘要	Significant synthetic challenges remain for the asymmetric synthesis of tertiary alpha-fluoro ketones, which are potentially useful molecules for the development of drugs, agrochemicals, and functional materials. Herein, we describe the development of a method for the catalytic enantioselective synthesis of tertiary alpha-fluoro ketones via the Tsuji-Trost reaction of racemic acyclic alpha-fluorinated ketones. Enantioenriched acyclic alpha-cabonyl tertiary fluorides can be produced with the aid of a palladium/phosphinooxazoline catalyst.
学科主题	氟化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1021/jo500923u
语种	英语
内容类型	期刊论文
源URL	[http://ir.sioc.ac.cn/handle/331003/38810]
专题	上海有机化学研究所_中科院有机氟化学重点实验室
作者单位	中科院上海有机化学研究所
推荐引用方式 GB/T 7714	Wang WG,Shen HM,Wan XL,et al. Enantioselective Pd-Catalyzed Allylation of Acyclic alpha-Fluorinated Ketones[J]. J. Org. Chem.,2014,79(13):6347-6353.
APA	王文贵,沈海明,万晓龙,陈庆云,&郭勇.(2014).Enantioselective Pd-Catalyzed Allylation of Acyclic alpha-Fluorinated Ketones.J. Org. Chem.,79(13),6347-6353.
MLA	王文贵,et al."Enantioselective Pd-Catalyzed Allylation of Acyclic alpha-Fluorinated Ketones".J. Org. Chem. 79.13(2014):6347-6353.