Facile Conversion of Cyclopropanols into Linear Conjugate Enones

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	Facile Conversion of Cyclopropanols into Linear Conjugate Enones
	Han WB(韩伟博); Li SG(李绍刚); Lu XW(陆晓伟); Wu YK(伍贻康)
刊名	Eur. J. Org. Chem.
	2014
卷号	2014 期号:18 页码:3841-3846
其他题名	将环丙基醇转化为开链共轭烯酮的简便方法
通讯作者	伍贻康
英文摘要	A practical method for the conversion of 1,2-disubstituted cyclopropanols derived from Kulinkovich cyclopropanation into linear enones was developed. The approach features regioselective cleavage of the cyclopropane rings in EtOH at ambient temperature with inexpensive and readily available Co(acac)2 as the catalyst and air as the reagent. The crude intermediate peroxides were directly reduced with Ph3P to afford the corresponding -hydroxy ketones, which, on mesylation and -elimination performed in a one-pot manner, furnished the end products in good to excellent yields after only one chromatography step at the end of the whole sequence.
学科主题	有机化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1002/ejoc.201402175
语种	英语
内容类型	期刊论文
源URL	[http://ir.sioc.ac.cn/handle/331003/38949]
专题	上海有机化学研究所_生命有机化学国家重点实验室
作者单位	中科院上海有机化学研究所
推荐引用方式 GB/T 7714	Han WB,Li SG,Lu XW,et al. Facile Conversion of Cyclopropanols into Linear Conjugate Enones[J]. Eur. J. Org. Chem.,2014,2014(18):3841-3846.
APA	韩伟博,李绍刚,陆晓伟,&伍贻康.(2014).Facile Conversion of Cyclopropanols into Linear Conjugate Enones.Eur. J. Org. Chem.,2014(18),3841-3846.
MLA	韩伟博,et al."Facile Conversion of Cyclopropanols into Linear Conjugate Enones".Eur. J. Org. Chem. 2014.18(2014):3841-3846.