Copper-Catalyzed Intermolecular Trifluoromethylarylation of Alkenes: Mutual Activation of Arylboronic Acid and CF3+ Reagent

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	Copper-Catalyzed Intermolecular Trifluoromethylarylation of Alkenes: Mutual Activation of Arylboronic Acid and CF3+ Reagent
	Wang F(王飞); Wang DH(王定海); Mu X(慕欣); Chen PH(陈品红); Liu GS(刘国生)
刊名	J. Am. Chem. Soc.
	2014
卷号	136 期号:29 页码:10202-10205
其他题名	铜催化烯烃的分子间三氟甲基芳基化反应: 芳基硼酸和CF3+试剂相互活化
通讯作者	刘国生
英文摘要	A novel copper-catalyzed intermolecular trifluoromethylarylation of alkenes is developed using less active ether-type Togni's reagent under mild reaction conditions. Various alkenes and diverse arylboronic acids are compatible with these conditions. Preliminary mechanistic studies reveal that a mutual activation process between arylboronic acid and CF3+ reagent is essential. In addition, the reaction might involve a rate-determining transmetalation, and the final aryl C-C bond is derived from reductive elimination of the aryl(alkyl)Cu(III) intermediate.
学科主题	金属有机化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1021/ja504458j
语种	英语
内容类型	期刊论文
源URL	[http://ir.sioc.ac.cn/handle/331003/39081]
专题	上海有机化学研究所_金属有机化学国家重点实验室
作者单位	中科院上海有机化学研究所
推荐引用方式 GB/T 7714	Wang F,Wang DH,Mu X,et al. Copper-Catalyzed Intermolecular Trifluoromethylarylation of Alkenes: Mutual Activation of Arylboronic Acid and CF3+ Reagent[J]. J. Am. Chem. Soc.,2014,136(29):10202-10205.
APA	王飞,王定海,慕欣,陈品红,&刘国生.(2014).Copper-Catalyzed Intermolecular Trifluoromethylarylation of Alkenes: Mutual Activation of Arylboronic Acid and CF3+ Reagent.J. Am. Chem. Soc.,136(29),10202-10205.
MLA	王飞,et al."Copper-Catalyzed Intermolecular Trifluoromethylarylation of Alkenes: Mutual Activation of Arylboronic Acid and CF3+ Reagent".J. Am. Chem. Soc. 136.29(2014):10202-10205.