Phosphine-catalyzed asymmetric [4+1] annulation of activated alpha,beta-unsaturated ketones with Morita-Baylis-Hillman carbonates: enantioselective synthesis of spirooxindoles containing two adjacent quaternary stereocenters

CORC > 上海有机化学研究所 > 中国科学院上海有机化学研究所 > 金属有机化学国家重点实验室

	Phosphine-catalyzed asymmetric [4+1] annulation of activated alpha,beta-unsaturated ketones with Morita-Baylis-Hillman carbonates: enantioselective synthesis of spirooxindoles containing two adjacent quaternary stereocenters
	Hu FL(胡方乐); Wei Y(魏音); Shi M(施敏)
刊名	Chem. Commun.
	2014
卷号	50 期号:64 页码:8912-8914
其他题名	膦催化的MBH产物和a,b-不饱和酮的[4+1]环加成反应, 高对映选择性地合成螺环氧化吲哚
通讯作者	施敏
英文摘要	The asymmetric [4+1] annulation of activated alpha,beta-unsaturated ketones with MBH carbonates catalyzed by bifunctional thiourea-phosphine catalysts derived from an axially chiral binaphthyl scaffold has been developed, giving spirooxindoles with two adjacent quaternary stereocenters in good yields with high enantioselectivities and moderate diastereoselectivities under mild conditions.
学科主题	金属有机化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1039/c4cc03479a
语种	英语
内容类型	期刊论文
源URL	[http://ir.sioc.ac.cn/handle/331003/39080]
专题	上海有机化学研究所_金属有机化学国家重点实验室
作者单位	中科院上海有机化学研究所
推荐引用方式 GB/T 7714	Hu FL,Wei Y,Shi M. Phosphine-catalyzed asymmetric [4+1] annulation of activated alpha,beta-unsaturated ketones with Morita-Baylis-Hillman carbonates: enantioselective synthesis of spirooxindoles containing two adjacent quaternary stereocenters[J]. Chem. Commun.,2014,50(64):8912-8914.
APA	胡方乐,魏音,&施敏.(2014).Phosphine-catalyzed asymmetric [4+1] annulation of activated alpha,beta-unsaturated ketones with Morita-Baylis-Hillman carbonates: enantioselective synthesis of spirooxindoles containing two adjacent quaternary stereocenters.Chem. Commun.,50(64),8912-8914.
MLA	胡方乐,et al."Phosphine-catalyzed asymmetric [4+1] annulation of activated alpha,beta-unsaturated ketones with Morita-Baylis-Hillman carbonates: enantioselective synthesis of spirooxindoles containing two adjacent quaternary stereocenters".Chem. Commun. 50.64(2014):8912-8914.