Chiral- Amine- Catalyzed Asymmetric Bromocyclization of Tryptamine Derivatives

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	Chiral- Amine- Catalyzed Asymmetric Bromocyclization of Tryptamine Derivatives
	Cai Q(蔡泉); Yin Q(殷勤); You SL(游书力)
刊名	Asian J. Org. Chem.
	2014
卷号	3 期号:4 页码:408-411
其他题名	手性胺催化的色胺衍生物的不对称溴环化
通讯作者	游书力
英文摘要	Chiral hexahydropyrro[2,3]indole (HPI) units exist widely in natural and unnatural products with significant biological activities. The enantioselective synthesis of brominated hexahydropyrrolo[2,3-b]indole (HPI) subunits by asymmetric bromocyclization of tryptamine derivatives catalyzed by a chiral amine has been realized. In the presence of hydroquinine 1,4-phthalazinediyl diether ((DHQ)(2)PHAL, 20mol%) and L-(-)-camphorsulfonic acid (20mol%), enantioenriched brominated HPI derivatives were obtained from readily available substituted tryptamines in up to 99% yield and 73%ee.
学科主题	金属有机化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1002/ajoc.201300146
语种	英语
内容类型	期刊论文
源URL	[http://ir.sioc.ac.cn/handle/331003/39062]
专题	上海有机化学研究所_金属有机化学国家重点实验室
作者单位	中科院上海有机化学研究所
推荐引用方式 GB/T 7714	Cai Q,Yin Q,You SL. Chiral- Amine- Catalyzed Asymmetric Bromocyclization of Tryptamine Derivatives[J]. Asian J. Org. Chem.,2014,3(4):408-411.
APA	蔡泉,殷勤,&游书力.(2014).Chiral- Amine- Catalyzed Asymmetric Bromocyclization of Tryptamine Derivatives.Asian J. Org. Chem.,3(4),408-411.
MLA	蔡泉,et al."Chiral- Amine- Catalyzed Asymmetric Bromocyclization of Tryptamine Derivatives".Asian J. Org. Chem. 3.4(2014):408-411.