Simultaneous speciation of selenium and mercury in human urine samples from long-term mercury-exposed populations with supplementation of selenium-enriched yeast by HPLC-ICP-MS

	Simultaneous speciation of selenium and mercury in human urine samples from long-term mercury-exposed populations with supplementation of selenium-enriched yeast by HPLC-ICP-MS
	Li YF(李玉锋); Chen CY(陈春英); Li B(李柏); Wang JX(王江雪); Gao YX(高愈希); Zhao YL(赵宇亮); Chai ZF(柴之芳); Li, YF; Chen, CY; Li, B
刊名	JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
	2007
卷号	22 期号:8 页码:925-930
通讯作者	Chinese Acad Sci, Key Lab Nucl Analyt Tech, Beijing 100049, Peoples R China ; Chinese Acad Sci, Lab Bioenvironm Effects Nanomat & Nanosafety, Inst High Energy Phys, Beijing 100049, Peoples R China ; Chinese Acad Sci, Natl Ctr Nanosci & Technol, Beijing 100049, Peoples R China ; Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China ; Natl Ctr Nanosci & Technol, Beijing 100080, Peoples R China ; Capital Normal Univ, Beijing 100037, Peoples R China
英文摘要	The present study was carried out to establish a method for simultaneous speciation analysis of selenium and mercury. Batch-wise elution using two different mobile phases that are suitable for selenium and mercury speciation leads to successful determination of both selenium and mercury standards in 30 minutes with good efficiency and resolution. The detection limits are in the range of 0.05 -0.3 mu g L-1 for selenium species, except TMSe, which has a poorer detection limit (1.48 mu g L-1), and 2.5 mu g L-1 for inorganic mercury (Hg2+) and 2.0 mu g L-1 for organic mercury (CH3Hg+). The method was applied to analysis of urine samples from people who were long-term mercury exposed and supplemented with selenium-enriched yeast for 90 days. Selenocystine (SeCys) was found to be a major selenium form, while inorganic mercury is the major mercury form. The recoveries of spiked species were between 93 and 117% in all cases. The increased mercury concentrations in urine after 90-day selenium supplementation suggest that selenium is beneficial to the excretion of mercury from urine. The proposed technique may help to increase our understanding of the in vivo interaction between selenium and mercury in human body.
学科主题	Chemistry; Spectroscopy
类目[WOS]	Chemistry, Analytical ; Spectroscopy
研究领域[WOS]	Chemistry ; Spectroscopy
原文出处	SCI
语种	英语
WOS记录号	WOS:000248281200010
内容类型	期刊论文
源URL	[http://ir.ihep.ac.cn/handle/311005/238747]
专题	高能物理研究所_院士高能物理研究所_实验物理中心高能物理研究所_多学科研究中心
作者单位	中国科学院高能物理研究所
推荐引用方式 GB/T 7714	Li YF,Chen CY,Li B,et al. Simultaneous speciation of selenium and mercury in human urine samples from long-term mercury-exposed populations with supplementation of selenium-enriched yeast by HPLC-ICP-MS[J]. JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY,2007,22(8):925-930.
APA	李玉锋.,陈春英.,李柏.,王江雪.,高愈希.,...&Chai, ZF.(2007).Simultaneous speciation of selenium and mercury in human urine samples from long-term mercury-exposed populations with supplementation of selenium-enriched yeast by HPLC-ICP-MS.JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY,22(8),925-930.
MLA	李玉锋,et al."Simultaneous speciation of selenium and mercury in human urine samples from long-term mercury-exposed populations with supplementation of selenium-enriched yeast by HPLC-ICP-MS".JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY 22.8(2007):925-930.