Element distribution in the brain of rats exposed to lanthanum measured by synchrotron radiation X-ray fluorescence

	Element distribution in the brain of rats exposed to lanthanum measured by synchrotron radiation X-ray fluorescence
	Feng LX(冯流星); Xiao HQ(肖海清); He X(何潇); Li ZJ(李子杰); Li FL(李福亮); Liu NQ(刘年庆); Chai ZF(柴之芳); Zhao YL(赵宇亮); Huang YY(黄宇营); He W(何伟)
刊名	JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
	2007
卷号	272 期号:2 页码:333-337
通讯作者	Chinese Acad Sci, Inst High Energy Phys, Key Lab Nucl Analyt Tech, Beijing 100049, Peoples R China ; Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China ; Beijing Synchrotron Radiat Facil, Beijing 100049, Peoples R China ; Shenzhen Univ, Inst Nucl Technol, Shenzhen 518060, Peoples R China
英文摘要	To investigate the effects of lanthanum exposure on regional distribution of inorganic elements in rat brain. Wistar rats were exposed to lanthanum chloride through oral administration at 0, 0.1, 2, and 40 mg/kg concentration for 6 months. The elements such as Cl, K, Ca, Fe, Cu, and Zn were identified in the brain slices by synchrotron radiation X-ray fluorescence (SRXRF) analysis. Differences of brain elemental distributions were noticed. Cl, Ca, and Zn were primarily concentrated in hippocampus of the controls. With the increase of the lanthanum dosage, the Ca and Zn levels significantly decreased, while the Cu levels significantly elevated in cortex, hippocampus and thalamus. Our results suggest that subchronic lanthanum exposure in rats appears to change elemental distributions in brain.
学科主题	Chemistry; Nuclear Science & Technology
类目[WOS]	Chemistry, Analytical ; Chemistry, Inorganic & Nuclear ; Nuclear Science & Technology
研究领域[WOS]	Chemistry ; Nuclear Science & Technology
原文出处	SCI
语种	英语
WOS记录号	WOS:000245360100026
内容类型	期刊论文
源URL	[http://ir.ihep.ac.cn/handle/311005/237026]
专题	高能物理研究所_院士高能物理研究所_多学科研究中心
作者单位	中国科学院高能物理研究所
推荐引用方式 GB/T 7714	Feng LX,Xiao HQ,He X,et al. Element distribution in the brain of rats exposed to lanthanum measured by synchrotron radiation X-ray fluorescence[J]. JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY,2007,272(2):333-337.
APA	冯流星.,肖海清.,何潇.,李子杰.,李福亮.,...&Zhang, ZY.(2007).Element distribution in the brain of rats exposed to lanthanum measured by synchrotron radiation X-ray fluorescence.JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY,272(2),333-337.
MLA	冯流星,et al."Element distribution in the brain of rats exposed to lanthanum measured by synchrotron radiation X-ray fluorescence".JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY 272.2(2007):333-337.