Ultrahigh reactivity and grave nanotoxicity of copper nanoparticles

	Ultrahigh reactivity and grave nanotoxicity of copper nanoparticles
	Meng H(孟幻); Chen Z(陈真); Xing GM(邢更妹); Yuan H(袁慧); Chen CY(陈春英); Zhao F(赵峰); Zhang CC(张程程); Wang Y(王云); Zhao YL(赵宇亮); Meng, H
刊名	JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
	2007
卷号	272 期号:3 页码:595-598
通讯作者	Chinese Acad Sci, Inst High Energy Phys, Lab Bioenvironm Hlth Sci Nanoscale Mat, Beijing 100049, Peoples R China ; Grad Univ Chinese Acad Sci, Beijing 100049, Peoples R China ; Natl Ctr Nanosci & Nanotechnol, Beijing 100081, Peoples R China
英文摘要	Recently, it was reported that the toxicity of copper particles increases with the decrease of the particle size on a mass basis. To understand this phenomenon, inductively coupled plasma mass spectrometry (ICP-MS) techniques and in vitro chemical studies were carried out to explore how they produce toxicity in vivo. The results suggest that when the sizes of particles become small and down to a nanoscale, copper becomes extremely reactive in a simulative intracorporeal environment. The nanosized copper particles consume the hydrogen ions in stomach more quickly than micron ones. These processes further convert the copper nanoparticles into cupric ions whose toxicity is very high in vivo.
学科主题	Chemistry; Nuclear Science & Technology
类目[WOS]	Chemistry, Analytical ; Chemistry, Inorganic & Nuclear ; Nuclear Science & Technology
研究领域[WOS]	Chemistry ; Nuclear Science & Technology
原文出处	SCI
语种	英语
WOS记录号	WOS:000246184200030
内容类型	期刊论文
源URL	[http://ir.ihep.ac.cn/handle/311005/238059]
专题	高能物理研究所_多学科研究中心高能物理研究所_加速器中心高能物理研究所_粒子天体物理中心
作者单位	中国科学院高能物理研究所
推荐引用方式 GB/T 7714	Meng H,Chen Z,Xing GM,et al. Ultrahigh reactivity and grave nanotoxicity of copper nanoparticles[J]. JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY,2007,272(3):595-598.
APA	孟幻.,陈真.,邢更妹.,袁慧.,陈春英.,...&Zhao, YL.(2007).Ultrahigh reactivity and grave nanotoxicity of copper nanoparticles.JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY,272(3),595-598.
MLA	孟幻,et al."Ultrahigh reactivity and grave nanotoxicity of copper nanoparticles".JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY 272.3(2007):595-598.