Diffraction-Enhanced Radiography of Various Mouse Organs

	Diffraction-Enhanced Radiography of Various Mouse Organs
	Zhang, X; Yang, XR; Chen, Y; Li, HQ; Liu, WY; Yuan, QX; Chen, SL; Yuan QX(袁清习)
刊名	AMERICAN JOURNAL OF ROENTGENOLOGY
	2010
卷号	195 期号:3 页码:545-549
关键词	bile ducts blood vessels diffraction-enhanced imaging synchrotron radiation
通讯作者	[Chen, Shao-Liang] Fudan Univ, Affiliated ZhongShan Hosp, Dept Nucl Med, Shanghai 200032, Peoples R China ; [Liu, Wen-Ya] Xinjiang Med Univ, Affiliated Hosp 1, Dept Radiol, Urumqi, Peoples R China ; [Li, Hai-Qing] Shanghai Jiao Tong Univ, Sch Med, Rui Jin Hosp, Shanghai 200030, Peoples R China ; [Chen, Yu ; Yuan, Qing-Xi] Chinese Acad Sci, Inst High Energy Phys, Beijing, Peoples R China ; [Yang, Xin-Rong] Fudan Univ, ZhongShan Hosp, Liver Canc Inst, Shanghai 200032, Peoples R China ; [Zhang, Xi] Fudan Univ, Shanghai Med Coll, Dept Oncol, Shanghai 200032, Peoples R China ; [Zhang, Xi] Fudan Univ, Affiliated Canc Hosp, Dept Radiol, Shanghai 200032, Peoples R China
英文摘要	OBJECTIVE. The purposes of this study were to evaluate whether a novel radiographic technique, diffraction-enhanced radiographic imaging, would render high-contrast images of mouse livers, hearts, and kidneys and to determine whether blood vessels and bile ducts can be differentiated on images of mouse livers. MATERIALS AND METHODS. For imaging of the bile ducts, mouse livers were excised 20 or 35 days after ligation of the common bile duct. Livers, hearts, and kidneys of control mice also were excised for imaging. The diffraction-enhanced imaging experiments were performed with a silicon 333 crystal diffraction plane and an 18-keV x-ray beam. The beam incident to the sample measured 20 mm (horizontal) x 11 mm (vertical). Images were acquired with the analyzer crystal set at different positions of the rocking curve. RESULTS. Only dilated bile ducts, no normal bile ducts, were found. With diffraction-enhanced imaging without a contrast agent, the blood vessels of the liver, heart, and kidney were visualized to a scale of tens of micrometers. CONCLUSION. Diffraction-enhanced imaging with a silicon 333 crystal plane had excellent contrast in the detection of blood vessels and pathologically dilated bile ducts and may be a promising radiographic technique for basic medical research.
学科主题	Radiology, Nuclear Medicine & Medical Imaging
类目[WOS]	Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]	Radiology, Nuclear Medicine & Medical Imaging
原文出处	SCI
语种	英语
WOS记录号	WOS:000281180500002
内容类型	期刊论文
源URL	[http://ir.ihep.ac.cn/handle/311005/237899]
专题	高能物理研究所_多学科研究中心
作者单位	中国科学院高能物理研究所
推荐引用方式 GB/T 7714	Zhang, X,Yang, XR,Chen, Y,et al. Diffraction-Enhanced Radiography of Various Mouse Organs[J]. AMERICAN JOURNAL OF ROENTGENOLOGY,2010,195(3):545-549.
APA	Zhang, X.,Yang, XR.,Chen, Y.,Li, HQ.,Liu, WY.,...&袁清习.(2010).Diffraction-Enhanced Radiography of Various Mouse Organs.AMERICAN JOURNAL OF ROENTGENOLOGY,195(3),545-549.
MLA	Zhang, X,et al."Diffraction-Enhanced Radiography of Various Mouse Organs".AMERICAN JOURNAL OF ROENTGENOLOGY 195.3(2010):545-549.