Self-Assembled Smart Nanocarriers for Targeted Drug Delivery

	Self-Assembled Smart Nanocarriers for Targeted Drug Delivery
	Cui, Wei 1; Li, Junbai 1; Decher, Gero 2,3
刊名	ADVANCED MATERIALS
	2016-02-10
卷号	28 期号:6 页码:1302-1311
关键词	molecular assembly nanostructure drug carriers selective recognition
英文摘要	Nanostructured drug-carrier systems promise numerous benefits for drug delivery. They can be engineered to precisely control drug-release rates or to target specific sites within the body with a specific amount of therapeutic agent. However, to achieve the best therapeutic effects, the systems should be designed for carrying the optimum amount of a drug to the desired target where it should be released at the optimum rate for a specified time. Despite numerous attempts, fulfilling all of these requirements in a synergistic way remains a huge challenge. The trend in drug delivery is consequently directed toward integrated multifunctional carrier systems, providing selective recognition in combination with sustained or triggered release. Capsules as vesicular systems enable drugs to be confined for controlled release. Furthermore, carriers modified with recognition groups can enhance the capability of encapsulated drug efficacy. Here, recent advances are reviewed regarding designing and preparing assembled capsules with targeting ligands or size controllable for selective recognition in drug delivery.
收录类别	SCI
语种	英语
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/33809]
专题	化学研究所_有机固体实验室
作者单位	1.Chinese Acad Sci, Inst Chem, Key Lab Colloid Interface & Chem Thermodynam, BNLMS, Beijing 100190, Peoples R China 2.Univ Strasbourg, Fac Chim, 1 Rue Blaise Pascal, F-67008 Strasbourg, France 3.Inst Charles Sadron, CNRS, 23 Rue Loess, F-67034 Strasbourg, France
推荐引用方式 GB/T 7714	Cui, Wei,Li, Junbai,Decher, Gero. Self-Assembled Smart Nanocarriers for Targeted Drug Delivery[J]. ADVANCED MATERIALS,2016,28(6):1302-1311.
APA	Cui, Wei,Li, Junbai,&Decher, Gero.(2016).Self-Assembled Smart Nanocarriers for Targeted Drug Delivery.ADVANCED MATERIALS,28(6),1302-1311.
MLA	Cui, Wei,et al."Self-Assembled Smart Nanocarriers for Targeted Drug Delivery".ADVANCED MATERIALS 28.6(2016):1302-1311.