Drug-Incorporated Electrospun Fibers Efficiently Prevent Postoperative Adhesion

	Drug-Incorporated Electrospun Fibers Efficiently Prevent Postoperative Adhesion
	Shi,Bo; Ding,Jianxun; Wei,Junchao; Fu,Changfeng; Zhuang,Xiuli; Chen,Xuesi
刊名	current pharmaceutical design
	2015
卷号	21 期号:15 页码:1960-1966
关键词	INTRAABDOMINAL ADHESIONS ABDOMINAL ADHESIONS FIBROUS MEMBRANES RAT MODEL PERITENDINOUS ADHESIONS POSTSURGICAL ADHESIONS TENDON ADHESIONS ANTIADHESION REDUCTION RELEASE
通讯作者	ding,jx
英文摘要	postoperative adhesion (poa) is a serious event that always causes chronic pain and functional obstruction. up to now, a variety of matrices prepared by diverse technologies have been employed as the physical barriers to prevent poa. among them, the electrospun fibers of biodegradable polymers exhibit more obvious advantages, such as large surface area, high porosity, and excellent anti-adhesion efficiency. however, the pure electrospun fibers for anti-adhesion cannot effectively regulate the cellular behaviors, and tissue inflammation and healing. in recent years, the polymeric electrospun fibers loaded with various drugs, such as antimicrobial agents, anti-inflammatory drugs, and healing accelerators, have been developed. the advanced anti-adhesion fibers play a more efficient role in the field of anti-adhesion, which can efficiently prevent poa and infection, tamp down inflammation, and promote the recovery of tissue function after surgery. this review highlights the recent development of anti-adhesion electrospun fibers loaded with various drugs, and presents the possible prospects.
收录类别	SCI
语种	英语
公开日期	2016-05-31
内容类型	期刊论文
源URL	[http://ir.ciac.jl.cn/handle/322003/67910]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Shi,Bo,Ding,Jianxun,Wei,Junchao,et al. Drug-Incorporated Electrospun Fibers Efficiently Prevent Postoperative Adhesion[J]. current pharmaceutical design,2015,21(15):1960-1966.
APA	Shi,Bo,Ding,Jianxun,Wei,Junchao,Fu,Changfeng,Zhuang,Xiuli,&Chen,Xuesi.(2015).Drug-Incorporated Electrospun Fibers Efficiently Prevent Postoperative Adhesion.current pharmaceutical design,21(15),1960-1966.
MLA	Shi,Bo,et al."Drug-Incorporated Electrospun Fibers Efficiently Prevent Postoperative Adhesion".current pharmaceutical design 21.15(2015):1960-1966.