Antimalarial diterpenoid dimers of a new carbon skeleton from Aphanamixis grandifolia

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	Antimalarial diterpenoid dimers of a new carbon skeleton from Aphanamixis grandifolia
	Zhang, Hua ; Liu, Jia ; Gan, Li-She ; Dalal, Seema ; Cassera, Maria B. ; Yue, Jian-Min
刊名	ORGANIC & BIOMOLECULAR CHEMISTRY
	2016
卷号	14 期号:3 页码:957-962
关键词	APHADILACTONES A-D STEM BARKS CHEMICAL-CONSTITUENTS FRUITS TRITERPENOIDS DERIVATIVES LIMONOIDS RING
ISSN号	1477-0520
中文摘要	Chemical investigation into the minor constituents of Aphanamixis grandifolia yielded three new diterpenoid dimers, aphadilactones E-G (1-3) featuring a new carbon skeleton. Their structures and absolute configurations were fully established by comprehensive spectroscopic data analysis and ECD calculation. Discovery of another two new dimers (4 and 5) suggested the structure of recently reported aphanamene A to be re-investigated. Compounds 1-5 showed moderate antimalarial activities with low micromolar IC50 values.
收录类别	SCI
原文出处	10.1039/c5ob02296g
语种	英语
公开日期	2016-05-12
内容类型	期刊论文
源URL	[http://ir.xtbg.org.cn/handle/353005/9800]
专题	西双版纳热带植物园_文献共享
推荐引用方式 GB/T 7714	Zhang, Hua,Liu, Jia,Gan, Li-She,et al. Antimalarial diterpenoid dimers of a new carbon skeleton from Aphanamixis grandifolia[J]. ORGANIC & BIOMOLECULAR CHEMISTRY,2016,14(3):957-962.
APA	Zhang, Hua,Liu, Jia,Gan, Li-She,Dalal, Seema,Cassera, Maria B.,&Yue, Jian-Min.(2016).Antimalarial diterpenoid dimers of a new carbon skeleton from Aphanamixis grandifolia.ORGANIC & BIOMOLECULAR CHEMISTRY,14(3),957-962.
MLA	Zhang, Hua,et al."Antimalarial diterpenoid dimers of a new carbon skeleton from Aphanamixis grandifolia".ORGANIC & BIOMOLECULAR CHEMISTRY 14.3(2016):957-962.