Investigation of spherical hydrogel surface with optical interferometer

	Investigation of spherical hydrogel surface with optical interferometer
	Zheng, Huizhen 1,4; Xie, Hongguo 1; Wu, Hao 1,4; Wang, Feng 3; Liu, Xiudong 2; Yu, Weiting 1; Ma, Xiaojun 1
刊名	colloids and surfaces a-physicochemical and engineering aspects
	2015-11-05
卷号	484 页码:457-462
关键词	Hydrogel microspheres Surface morphology Optical interferometer In wet In situ
英文摘要	surface morphology of calcium alginate hydrogel microspheres (cahm) with ultrahigh water content has been found to affect the interaction with proteins and cells in vivo. in this study, an optical interferometer is developed to firstly characterize spherical surface morphology of cahm in wet and in situ under normal pressure and temperature. cahm shows smoother surface with significant lower roughness than flat alginate membrane, which also contribute to significantly different surface morphology between spherical microcapsules and flat membrane after coating with chitosan. these results help to update the previous knowledge that flat surface can be used to simulate spherical surface for understanding hydrogel behavior to protein adsorption. meanwhile, cahm is characterized by sem techniques with drying process at varying degrees, which demonstrates deviated surface morphology to the original wet surface. therefore, the optical interferometer is proved a useful tool to acquire the authentic and accurate surface information of spherical hydrogels at applied wet state. (c) 2015 elsevier b.v. all rights reserved.
WOS标题词	science & technology ; physical sciences
类目[WOS]	chemistry, physical
研究领域[WOS]	chemistry
关键词[WOS]	alginate ; chitosan ; beads
收录类别	SCI
语种	英语
WOS记录号	WOS:000362130100053
公开日期	2016-05-09
内容类型	期刊论文
源URL	[http://cas-ir.dicp.ac.cn/handle/321008/146573]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Chinese Acad Sci, Dalian Inst Chem Phys, Lab Biomed Mat Engn, Dalian 116023, Peoples R China 2.Dalian Univ, Coll Environm & Chem Engn, Dalian Econ Technol Dev Zone, Dalian 116622, Peoples R China 3.Chinese Acad Sci, Dalian Inst Chem Phys, Lab Opt Fabricat & Coating, Dalian 116023, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Zheng, Huizhen,Xie, Hongguo,Wu, Hao,et al. Investigation of spherical hydrogel surface with optical interferometer[J]. colloids and surfaces a-physicochemical and engineering aspects,2015,484:457-462.
APA	Zheng, Huizhen.,Xie, Hongguo.,Wu, Hao.,Wang, Feng.,Liu, Xiudong.,...&Ma, Xiaojun.(2015).Investigation of spherical hydrogel surface with optical interferometer.colloids and surfaces a-physicochemical and engineering aspects,484,457-462.
MLA	Zheng, Huizhen,et al."Investigation of spherical hydrogel surface with optical interferometer".colloids and surfaces a-physicochemical and engineering aspects 484(2015):457-462.