A Porphyrin-Inspired Iron Catalyst for Asymmetric Epoxidation of Electron-Deficient Olefins

	A Porphyrin-Inspired Iron Catalyst for Asymmetric Epoxidation of Electron-Deficient Olefins
	Dai, Wen 1,2; Li, Guosong 1,2; Chen, Bo 1,2; Wang, Lianyue 1,2; Gao, Shuang 1,2
刊名	organic letters
	2015-02-20
卷号	17 期号:4 页码:904-907
英文摘要	an in situ formed porphyrin-inspired iron complex that catalyzes asymmetric epoxidation of di- and trisubstituted enones is described. the reaction provides highly enantioenriched alpha,beta-epoxyketones (up to 99% ee). the practical utility of the new catalyst system is demonstrated by the gram-scale synthesis of optically pure epoxide. hammett analysis suggests that the transition state of the reaction is electron-demanding and the active oxidant is electrophilic.
WOS标题词	science & technology ; physical sciences
类目[WOS]	chemistry, organic
研究领域[WOS]	chemistry
关键词[WOS]	highly enantioselective epoxidation ; aqueous hydrogen-peroxide ; wide substrate scope ; alpha,beta-unsaturated ketones ; manganese complex ; beta,beta-disubstituted enones ; stereoselective epoxidation ; unfunctionalized olefins ; oxidation catalysis ; terminal olefins
收录类别	SCI
语种	英语
WOS记录号	WOS:000349942600036
公开日期	2016-05-09
内容类型	期刊论文
源URL	[http://cas-ir.dicp.ac.cn/handle/321008/146029]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China 2.Chinese Acad Sci, Dalian Natl Lab Clean Energy, Dalian 116023, Peoples R China
推荐引用方式 GB/T 7714	Dai, Wen,Li, Guosong,Chen, Bo,et al. A Porphyrin-Inspired Iron Catalyst for Asymmetric Epoxidation of Electron-Deficient Olefins[J]. organic letters,2015,17(4):904-907.
APA	Dai, Wen,Li, Guosong,Chen, Bo,Wang, Lianyue,&Gao, Shuang.(2015).A Porphyrin-Inspired Iron Catalyst for Asymmetric Epoxidation of Electron-Deficient Olefins.organic letters,17(4),904-907.
MLA	Dai, Wen,et al."A Porphyrin-Inspired Iron Catalyst for Asymmetric Epoxidation of Electron-Deficient Olefins".organic letters 17.4(2015):904-907.