Facile construction of macroporous hybrid monoliths via thiol-methacrylate Michael addition click reaction for capillary liquid chromatography

	Facile construction of macroporous hybrid monoliths via thiol-methacrylate Michael addition click reaction for capillary liquid chromatography
	Lin, Hui 1,2; Ou, Junjie 1; Liu, Zhongshan 1,2; Wang, Hongwei 1,2; Dong, Jing 1; Zou, Hanfa 1
刊名	journal of chromatography a
	2015-01-30
卷号	1379 页码:34-42
关键词	Polyhedral oligomeric silsesquioxane (POSS) Hybrid monolith Thiol-methacrylate Michael addition reaction Click chemistry Capillary liquid chromatography
英文摘要	a facile approach based on thiol-methacrylate michael addition click reaction was developed for construction of porous hybrid monolithic materials. three hybrid monoliths were prepared via thiol-methacrylate click polymerization by using methacrylate-polyhedral oligomeric silsesquioxane (poss) (cage mixture, n = 8, 10, 12, poss-ma) and three multi-thiol crosslinkers, 1,6-hexanedithiol (hdt), trimethylolpropane tris(3-mercaptopropionate) (tptm) and pentaerythritol tetrakis(3-mercaptopropionate) (ptm), respectively, in the presence of porogenic solvents (n-propanol and peg 200) and a catalyst (dimethylphenylphosphine, dmpp). the obtained monoliths possessed high thermal and chemical stabilities. besides, they all exhibited high column efficiencies and excellent separation abilities in capillary liquid chromatography (clc). the highest column efficiency could reach ca. 195,000 n/m for butylbenzene on the monolith prepared with poss-ma and tptm (monolith poss-tptm) in reversed-phase (rp) mode at 0.64 mm/s. good chromatographic performance were all achieved in the separations of polycyclic aromatic hydrocarbons (pahs), phenols, anilines, epa 610 as well as bovine serum albumin (bsa) digest. the high column efficiencies in the range of 51,400-117,000 n/m (achieved on the monolith poss-ptm in rp mode) convincingly demonstrated the high separation abilities of these thiol-methacrylate based hybrid monoliths. all the results demonstrated the feasibility of the phosphines catalyzed thiol-methacrylate michael addition click reaction in fabrication of monolithic columns with high efficiency for clc applications. (c) 2014 elsevier b.v. all rights reserved.
WOS标题词	science & technology ; life sciences & biomedicine ; physical sciences
类目[WOS]	biochemical research methods ; chemistry, analytical
研究领域[WOS]	biochemistry & molecular biology ; chemistry
关键词[WOS]	polyhedral oligomeric silsesquioxanes ; ring-opening polymerization ; stationary-phase ; silica monoliths ; columns ; chemistry ; electrochromatography ; performance ; separation ; photopolymerization
收录类别	SCI
语种	英语
WOS记录号	WOS:000349197300005
公开日期	2016-05-09
内容类型	期刊论文
源URL	[http://cas-ir.dicp.ac.cn/handle/321008/145936]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Chinese Acad Sci, Dalian Inst Chem Phys, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Lin, Hui,Ou, Junjie,Liu, Zhongshan,et al. Facile construction of macroporous hybrid monoliths via thiol-methacrylate Michael addition click reaction for capillary liquid chromatography[J]. journal of chromatography a,2015,1379:34-42.
APA	Lin, Hui,Ou, Junjie,Liu, Zhongshan,Wang, Hongwei,Dong, Jing,&Zou, Hanfa.(2015).Facile construction of macroporous hybrid monoliths via thiol-methacrylate Michael addition click reaction for capillary liquid chromatography.journal of chromatography a,1379,34-42.
MLA	Lin, Hui,et al."Facile construction of macroporous hybrid monoliths via thiol-methacrylate Michael addition click reaction for capillary liquid chromatography".journal of chromatography a 1379(2015):34-42.