Glucuronidation of aurantio-obtusin: identification of human UDP-glucuronosyltransferases and species differences

	Glucuronidation of aurantio-obtusin: identification of human UDP-glucuronosyltransferases and species differences
	Mi, Bao-Li 1; Sun, Qi 2; Qu, Yan-Qing 3; Gao, Xiao-Xu 1; Yu, Zhen-Wen 1; Ge, Guang-Bo 4; Cai, Shan-Shan 1; Zhang, Jie 1; Zheng, Yan-Chao 1; Zhang, Zhen-Qiu 1
刊名	xenobiotica
	2014-08-01
卷号	44 期号:8 页码:716-721
关键词	Aurantio-obtusin species difference UDP-glucuronosyltransferase (UGT)
英文摘要	1. the aurantio-obtusin's glucuronide was detected when aurantio-obtusin was incubated with human liver microsomes (hlms). recombinant ugt isoforms screening experiment showed that ugt1a8 was the major isoform contributed to the glucuronidation.
WOS标题词	science & technology ; life sciences & biomedicine
类目[WOS]	pharmacology & pharmacy ; toxicology
研究领域[WOS]	pharmacology & pharmacy ; toxicology
关键词[WOS]	metabolism ; bioavailability ; elucidation
收录类别	SCI
语种	英语
WOS记录号	WOS:000339564100005
公开日期	2016-05-09
内容类型	期刊论文
源URL	[http://cas-ir.dicp.ac.cn/handle/321008/145663]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Liaoning Univ Tradit Chinese Med, Pharmaceut Coll, Dalian 116600, Peoples R China 2.JiLin Aodong Med Ind Grp Co Ltd, Dept Res & Dev, Dunhua, Peoples R China 3.Yantaishan Hosp, Yantai, Shandong, Peoples R China 4.Chinese Acad Sci, Dalian Inst Chem Phys, Lab Pharmaceut Resource Discovery, Dalian, Peoples R China
推荐引用方式 GB/T 7714	Mi, Bao-Li,Sun, Qi,Qu, Yan-Qing,et al. Glucuronidation of aurantio-obtusin: identification of human UDP-glucuronosyltransferases and species differences[J]. xenobiotica,2014,44(8):716-721.
APA	Mi, Bao-Li.,Sun, Qi.,Qu, Yan-Qing.,Gao, Xiao-Xu.,Yu, Zhen-Wen.,...&Zhang, Zhen-Qiu.(2014).Glucuronidation of aurantio-obtusin: identification of human UDP-glucuronosyltransferases and species differences.xenobiotica,44(8),716-721.
MLA	Mi, Bao-Li,et al."Glucuronidation of aurantio-obtusin: identification of human UDP-glucuronosyltransferases and species differences".xenobiotica 44.8(2014):716-721.