Recent advances in stable isotope labeling based techniques for proteome relative quantification

	Recent advances in stable isotope labeling based techniques for proteome relative quantification
	Zhou, Yuan; Shan, Yichu; Zhang, Lihua; Zhang, Yukui
刊名	journal of chromatography a
	2014-10-24
卷号	1365 期号:1 页码:1-11
关键词	Proteome Relative quantification Stable isotope labeling Metabolic labeling Chemical labeling Enzyme-catalyzed labeling
通讯作者	张丽华
英文摘要	the large scale relative quantification of all proteins expressed in biological samples under different states is of great importance for discovering proteins with important biological functions, as well as screening disease related biomarkers and drug targets. therefore, the accurate quantification of proteins at proteome level has become one of the key issues in protein science. herein, the recent advances in stable isotope labeling based techniques for proteome relative quantification were reviewed, from the aspects of metabolic labeling, chemical labeling and enzyme-catalyzed labeling. furthermore, the future research direction in this field was prospected. (c) 2014 elsevier b.v. all rights reserved.
学科主题	物理化学
WOS标题词	science & technology ; life sciences & biomedicine ; physical sciences
类目[WOS]	biochemical research methods ; chemistry, analytical
研究领域[WOS]	biochemistry & molecular biology ; chemistry
关键词[WOS]	multiplexed quantitative proteomics ; coded affinity tags ; mass-spectrometry ; accurate quantitation ; cell-culture ; amino-acids ; in-vivo ; peptide ; proteins ; silac
收录类别	SCI
语种	英语
WOS记录号	WOS:000343618600001
公开日期	2016-05-09
内容类型	期刊论文
源URL	[http://cas-ir.dicp.ac.cn/handle/321008/144413]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	Chinese Acad Sci, Dalian Inst Chem Phys, Key Lab Separat Sci Analyt Chem, Natl Chromatog R&A Ctr, Dalian 116023, Peoples R China
推荐引用方式 GB/T 7714	Zhou, Yuan,Shan, Yichu,Zhang, Lihua,et al. Recent advances in stable isotope labeling based techniques for proteome relative quantification[J]. journal of chromatography a,2014,1365(1):1-11.
APA	Zhou, Yuan,Shan, Yichu,Zhang, Lihua,&Zhang, Yukui.(2014).Recent advances in stable isotope labeling based techniques for proteome relative quantification.journal of chromatography a,1365(1),1-11.
MLA	Zhou, Yuan,et al."Recent advances in stable isotope labeling based techniques for proteome relative quantification".journal of chromatography a 1365.1(2014):1-11.