Asymmetric Hydrogenation via Capture of Active Intermediates Generated from Aza-Pinacol Rearrangement

	Asymmetric Hydrogenation via Capture of Active Intermediates Generated from Aza-Pinacol Rearrangement
	Yu, Chang-Bin 1; Huang, Wen-Xue 1; Shi, Lei 1; Chen, Mu-Wang 1; Wu, Bo 1; Zhou, Yong-Gui 1,2
刊名	journal of the american chemical society
	2014-11-12
卷号	136 期号:45 页码:15837-15840
通讯作者	周永贵
英文摘要	an efficient palladium-catalyzed asymmetric hydrogenation via capture of an active intermediate generated in situ from acid-catalyzed aza-pinacol rearrangement has been successfully developed, providing efficient access to chiral exocyclic amines with up to 98% ee. three-, four-, and five-membered cyclic n-sulfonyl amino alcohols are viable substrates. this study opens a new window to the application of asymmetric hydrogenation.
学科主题	物理化学
WOS标题词	science & technology ; physical sciences
类目[WOS]	chemistry, multidisciplinary
研究领域[WOS]	chemistry
关键词[WOS]	c bond formation ; ruthenium-catalyzed hydrohydroxyalkylation ; aldehyde oxidation level ; semipinacol rearrangement ; enantioselective approach ; forming hydrogenation ; allylic alcohols ; bronsted acids ; facile access ; imines
收录类别	SCI ; IC ; CCR
语种	英语
WOS记录号	WOS:000344906100008
公开日期	2016-05-09
内容类型	期刊论文
源URL	[http://cas-ir.dicp.ac.cn/handle/321008/144100]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Chinese Acad Sci, Dalian Inst Chem Phys, State Key Lab Catalysis, Dalian 116023, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China
推荐引用方式 GB/T 7714	Yu, Chang-Bin,Huang, Wen-Xue,Shi, Lei,et al. Asymmetric Hydrogenation via Capture of Active Intermediates Generated from Aza-Pinacol Rearrangement[J]. journal of the american chemical society,2014,136(45):15837-15840.
APA	Yu, Chang-Bin,Huang, Wen-Xue,Shi, Lei,Chen, Mu-Wang,Wu, Bo,&Zhou, Yong-Gui.(2014).Asymmetric Hydrogenation via Capture of Active Intermediates Generated from Aza-Pinacol Rearrangement.journal of the american chemical society,136(45),15837-15840.
MLA	Yu, Chang-Bin,et al."Asymmetric Hydrogenation via Capture of Active Intermediates Generated from Aza-Pinacol Rearrangement".journal of the american chemical society 136.45(2014):15837-15840.