A flavone-based turn-on fluorescent probe for intracellular cysteine/homocysteine sensing with high selectivity

	A flavone-based turn-on fluorescent probe for intracellular cysteine/homocysteine sensing with high selectivity
	Zhang, Jian 1; Lv, Yanlin 1; Zhang, Wei 2; Ding, Hui 1; Liu, Rongji 3; Zhao, Yongsheng 2; Zhang, Guangjin 3; Tian, Zhiyuan 1
刊名	TALANTA
	2016
卷号	146 页码:41-48
关键词	Fluorescent probe Cysteine/homocysteine Bioimaging
英文摘要	A new type of flavone-based fluorescent probe (DMAF) capable of cysteine (Cys)/homocysteine (Hcy) sensing with high selectivity over other amino acids was developed. Such type of probe undergoes Cys/Hcy-mediated cyclization reaction with the involvement of its aldehyde group, which suppresses of the photoinduced electron transfer (PET) process of the probe molecule and consequently leads to the enhancement of fluorescence emission upon excitation using visible light. The formation of product of the Cys/Hcy-mediated cyclization reaction was confirmed and the preliminary fluorescence imaging experiments revealed the biocompatibility of the as-prepared probe and validated its practicability for intracellular Cys/Hcy sensing. (C) 2015 Elsevier B.V. All rights reserved.
收录类别	SCI
语种	英语
公开日期	2016-05-09
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/29186]
专题	化学研究所_光化学实验室
作者单位	1.UCAS, Sch Chem & Chem Engn, Beijing 100049, PR, Peoples R China 2.Chinese Acad Sci, BNLMS, Inst Chem, Key Lab Photochem, Beijing 100190, Peoples R China 3.Chinese Acad Sci, Key Lab Green Proc & Engn, Beijing Key Lab Ion Liquids Clean Proc, Inst Proc Engn, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Jian,Lv, Yanlin,Zhang, Wei,et al. A flavone-based turn-on fluorescent probe for intracellular cysteine/homocysteine sensing with high selectivity[J]. TALANTA,2016,146:41-48.
APA	Zhang, Jian.,Lv, Yanlin.,Zhang, Wei.,Ding, Hui.,Liu, Rongji.,...&Tian, Zhiyuan.(2016).A flavone-based turn-on fluorescent probe for intracellular cysteine/homocysteine sensing with high selectivity.TALANTA,146,41-48.
MLA	Zhang, Jian,et al."A flavone-based turn-on fluorescent probe for intracellular cysteine/homocysteine sensing with high selectivity".TALANTA 146(2016):41-48.