Conjugated Polymer-Based Hybrid Nanoparticles with Two-Photon Excitation and Near-Infrared Emission Features for Fluorescence Bioimaging within the Biological Window

	Conjugated Polymer-Based Hybrid Nanoparticles with Two-Photon Excitation and Near-Infrared Emission Features for Fluorescence Bioimaging within the Biological Window
	Lv, Yanlin 1; Liu, Peng 2; Ding, Hui 1; Wu, Yishi 3,4; Yan, Yongli 3,4; Liu, Heng 1; Wang, Xuefei 1; Huang, Fei 2; Zhao, Yongsheng 3,4; Tian, Zhiyuan 1
刊名	ACS APPLIED MATERIALS & INTERFACES
	2015-09-23
卷号	7 期号:37 页码:20640-20648
关键词	two-photon absorption near-infrared (NIR) fluorescence multiphoton fluorescence bioimaging energy transfer conjugated polymer
英文摘要	Hybrid fluorescent nanoparticles (NPs) capable of fluorescing near-infrared (NIR) light (centered similar to 730 nm) upon excitation of 800 nm laser light were constructed. A new type of conjugated polymer with two-photon excited fluorescence (TPEF) feature, P-F8-DPSB, was used as the NIR-light harvesting component and the energy donor while a NIR fluorescent dye, DPA-PR-PDI, was used as the energy acceptor and the NIR-light emitting component for the construction of the fluorescent NPs. The hybrid NPs possess delta value up to 2.3 x 10(6) GM per particle upon excitation of 800 nm pulse laser. The excellent two-photon absorption (TPA) property of the conjugated polymer component, together with its high fluorescence quantum yield (phi) up to 45% and the efficient energy transfer from the conjugated polymer to NIR-emitting fluorophore with efficiency up to 90%, imparted the hybrid NPs with TPEF-based NIR-input-NIR-output fluorescence imaging ability with penetration depth up to 1200 mu m. The practicability of the hybrid NPs for fluorescence imaging in Hela cells was validated.
收录类别	SCI
语种	英语
公开日期	2016-05-09
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/28827]
专题	化学研究所_光化学实验室
作者单位	1.UCAS, Sch Chem & Chem Engn, Beijing 100049, Peoples R China 2.S China Univ Technol, State Key Lab Luminescent Mat & Devices, Inst Polymer Optoelect Mat & Devices, Guangzhou 510640, Guangdong, Peoples R China 3.Chinese Acad Sci, Inst Chem, BNLMS, Beijing 100190, Peoples R China 4.Chinese Acad Sci, Key Lab Photochem, Inst Chem, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Lv, Yanlin,Liu, Peng,Ding, Hui,et al. Conjugated Polymer-Based Hybrid Nanoparticles with Two-Photon Excitation and Near-Infrared Emission Features for Fluorescence Bioimaging within the Biological Window[J]. ACS APPLIED MATERIALS & INTERFACES,2015,7(37):20640-20648.
APA	Lv, Yanlin.,Liu, Peng.,Ding, Hui.,Wu, Yishi.,Yan, Yongli.,...&Tian, Zhiyuan.(2015).Conjugated Polymer-Based Hybrid Nanoparticles with Two-Photon Excitation and Near-Infrared Emission Features for Fluorescence Bioimaging within the Biological Window.ACS APPLIED MATERIALS & INTERFACES,7(37),20640-20648.
MLA	Lv, Yanlin,et al."Conjugated Polymer-Based Hybrid Nanoparticles with Two-Photon Excitation and Near-Infrared Emission Features for Fluorescence Bioimaging within the Biological Window".ACS APPLIED MATERIALS & INTERFACES 7.37(2015):20640-20648.