Conjugated Polymer-Based Hybrid Nanoparticles with Two-Photon Excitation and Near-Infrared Emission Features for Fluorescence Bioimaging within the Biological Window | |
Lv, Yanlin1; Liu, Peng2; Ding, Hui1; Wu, Yishi3,4; Yan, Yongli3,4; Liu, Heng1; Wang, Xuefei1; Huang, Fei2; Zhao, Yongsheng3,4; Tian, Zhiyuan1 | |
刊名 | ACS APPLIED MATERIALS & INTERFACES
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2015-09-23 | |
卷号 | 7期号:37页码:20640-20648 |
关键词 | two-photon absorption near-infrared (NIR) fluorescence multiphoton fluorescence bioimaging energy transfer conjugated polymer |
英文摘要 | Hybrid fluorescent nanoparticles (NPs) capable of fluorescing near-infrared (NIR) light (centered similar to 730 nm) upon excitation of 800 nm laser light were constructed. A new type of conjugated polymer with two-photon excited fluorescence (TPEF) feature, P-F8-DPSB, was used as the NIR-light harvesting component and the energy donor while a NIR fluorescent dye, DPA-PR-PDI, was used as the energy acceptor and the NIR-light emitting component for the construction of the fluorescent NPs. The hybrid NPs possess delta value up to 2.3 x 10(6) GM per particle upon excitation of 800 nm pulse laser. The excellent two-photon absorption (TPA) property of the conjugated polymer component, together with its high fluorescence quantum yield (phi) up to 45% and the efficient energy transfer from the conjugated polymer to NIR-emitting fluorophore with efficiency up to 90%, imparted the hybrid NPs with TPEF-based NIR-input-NIR-output fluorescence imaging ability with penetration depth up to 1200 mu m. The practicability of the hybrid NPs for fluorescence imaging in Hela cells was validated. |
收录类别 | SCI |
语种 | 英语 |
公开日期 | 2016-05-09 |
内容类型 | 期刊论文 |
源URL | [http://ir.iccas.ac.cn/handle/121111/28827] ![]() |
专题 | 化学研究所_光化学实验室 |
作者单位 | 1.UCAS, Sch Chem & Chem Engn, Beijing 100049, Peoples R China 2.S China Univ Technol, State Key Lab Luminescent Mat & Devices, Inst Polymer Optoelect Mat & Devices, Guangzhou 510640, Guangdong, Peoples R China 3.Chinese Acad Sci, Inst Chem, BNLMS, Beijing 100190, Peoples R China 4.Chinese Acad Sci, Key Lab Photochem, Inst Chem, Beijing 100190, Peoples R China |
推荐引用方式 GB/T 7714 | Lv, Yanlin,Liu, Peng,Ding, Hui,et al. Conjugated Polymer-Based Hybrid Nanoparticles with Two-Photon Excitation and Near-Infrared Emission Features for Fluorescence Bioimaging within the Biological Window[J]. ACS APPLIED MATERIALS & INTERFACES,2015,7(37):20640-20648. |
APA | Lv, Yanlin.,Liu, Peng.,Ding, Hui.,Wu, Yishi.,Yan, Yongli.,...&Tian, Zhiyuan.(2015).Conjugated Polymer-Based Hybrid Nanoparticles with Two-Photon Excitation and Near-Infrared Emission Features for Fluorescence Bioimaging within the Biological Window.ACS APPLIED MATERIALS & INTERFACES,7(37),20640-20648. |
MLA | Lv, Yanlin,et al."Conjugated Polymer-Based Hybrid Nanoparticles with Two-Photon Excitation and Near-Infrared Emission Features for Fluorescence Bioimaging within the Biological Window".ACS APPLIED MATERIALS & INTERFACES 7.37(2015):20640-20648. |
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