Preparation of phenylboronate affinity rigid monolith with macromolecular porogen

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	Preparation of phenylboronate affinity rigid monolith with macromolecular porogen
	Li, Xiang-Jie; Jia, Man; Zhao, Yong-Xin; Liu, Zhao-Sheng; Akber Aisa, Haji
刊名	JOURNAL OF CHROMATOGRAPHY A
	2016
卷号	1438 期号:3 页码:171-178
关键词	Flavonol glycosides HPLC Macromolecular porogen Monolithic column Phenylboronate affinity monolith Solid phase extraction
通讯作者	Liu, ZS
英文摘要	Boronate-affinity monolithic column was first prepared via polystyrene (PS) as porogen in this work. The monolithic polymer was synthetized using 4-vinylphenylboronic acid (4-VPBA) as functional monomer, ethylene glycol dimethacrylate (EDMA) as crosslinker monomer, and a mixture of PS solution in tetrahydrofuran, the linear macromolecular porogen, and toluene as porogen. Isoquercitrin (ISO) and hyperoside (HYP), isomer diol flavonoid glycosides, can be baseline separated on the poly(VPBA-co-EDMA) monolith. The effect of polymerization variables on the selectivity factor, e.g., the ratio of monomer to crosslinker (M/C), the amount of PS and the molecular weight of macromolecular porogen was investigated. The surface properties of the monolithic polymer were characterized by scanning electron microscopy and nitrogen adsorption. The best polymerization condition was the M/C ratio of 7:3, and the PS concentration of 40mg/ml. The poly(VPBA-co-EDMA) polymer was also applied to extract cis-diol flavonoid glycosides from the crude extraction of cotton flower. After treated by poly(VPBA-co-EDMA) for solid phase extraction, high purity ISO and HYP (>99.96%) can be obtained with recovery of 83.7% and 78.6%, respectively.
收录类别	SCI
WOS记录号	WOS:000371941500018
内容类型	期刊论文
源URL	[http://ir.xjipc.cas.cn/handle/365002/4353]
专题	新疆理化技术研究所_资源化学研究室
作者单位	Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Urumqi 830011, Xinjiang, Peoples R China;Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, State Key Lab Basis Xinjiang Indigenous Med Plant, Urumqi 830011, Peoples R China;Univ Chinese Acad Sci, Beijing 100039, Peoples R China
推荐引用方式 GB/T 7714	Li, Xiang-Jie,Jia, Man,Zhao, Yong-Xin,et al. Preparation of phenylboronate affinity rigid monolith with macromolecular porogen[J]. JOURNAL OF CHROMATOGRAPHY A,2016,1438(3):171-178.
APA	Li, Xiang-Jie,Jia, Man,Zhao, Yong-Xin,Liu, Zhao-Sheng,&Akber Aisa, Haji.(2016).Preparation of phenylboronate affinity rigid monolith with macromolecular porogen.JOURNAL OF CHROMATOGRAPHY A,1438(3),171-178.
MLA	Li, Xiang-Jie,et al."Preparation of phenylboronate affinity rigid monolith with macromolecular porogen".JOURNAL OF CHROMATOGRAPHY A 1438.3(2016):171-178.