Synergistic Acid-Catalyzed Synthesis of N-Aryl-Substituted Azacycles from Anilines and Cyclic Ethers | |
Zhang ZB(张震北)1,2; Miao CX(苗成霞)1; Xia CG(夏春谷)1; Sun W(孙伟)1 | |
刊名 | Organic Letters |
2016 | |
卷号 | 18期号:7页码:1522-1525 |
ISSN号 | 1523-7060 |
通讯作者 | 孙伟 |
英文摘要 | A metal-free and efficient approach to N-aryl-substituted azacycles from arylamines and cyclic ethers is described. In this synthesis, the synergistic effect between Lewis and Brønsted acids is crucial to the ring-opening of cyclic ethers and the subsequent cyclization. The use of B(C6F5)3 enabled the formation of frustrated Lewis pairs (FLPs) from the reactants, and the resulting FLPs allowed ready access to the N-arylazacycles in moderate to good yields via further cyclization. Water is the sole waste resulting from the reaction, thereby making it an environmentally benign process. |
学科主题 | 物理化学与绿色催化 |
收录类别 | SCI |
资助信息 | the National Natural Science Foundation of China (Nos. 21473226;21133011) |
语种 | 英语 |
WOS记录号 | WOS:000373519600007 |
内容类型 | 期刊论文 |
源URL | [http://210.77.64.217/handle/362003/19476] |
专题 | 兰州化学物理研究所_OSSO国家重点实验室 |
作者单位 | 1.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
推荐引用方式 GB/T 7714 | Zhang ZB,Miao CX,Xia CG,et al. Synergistic Acid-Catalyzed Synthesis of N-Aryl-Substituted Azacycles from Anilines and Cyclic Ethers[J]. Organic Letters,2016,18(7):1522-1525. |
APA | Zhang ZB,Miao CX,Xia CG,&Sun W.(2016).Synergistic Acid-Catalyzed Synthesis of N-Aryl-Substituted Azacycles from Anilines and Cyclic Ethers.Organic Letters,18(7),1522-1525. |
MLA | Zhang ZB,et al."Synergistic Acid-Catalyzed Synthesis of N-Aryl-Substituted Azacycles from Anilines and Cyclic Ethers".Organic Letters 18.7(2016):1522-1525. |
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