Preliminary simulation studies on a cylindrical PEM scanner using GATE

	Preliminary simulation studies on a cylindrical PEM scanner using GATE
	Yan Q(闫强); Gao J(高娟); Dan BC(单保慈); Wei L(魏龙); Yan, Q; Gao, J; Shan, BC; Wei, L
刊名	CHINESE PHYSICS C
	2010
卷号	34 期号:1 页码:#REF!
关键词	simulation GATE cylindrical PEM evaluation
通讯作者	Yan, Q (reprint author), Chinese Acad Sci, Inst High Energy Phys, Key Lab Nucl Anal Tech, Beijing 100049, Peoples R China.
英文摘要	In this paper, we investigate the performance of a cylindrical positron emission mammography (PEM) by simulation, in order to estimate its feasibility before implementation. A well-developed simulation package, Geant4 Application for Tomographic Emission (GATE), is used to simulate the scanner geometry and physical processes. The simulated PEM scanner is composed of 64 blocks axially arranged in 4 rings with an axial field-of-view (AFOV) of 12.8 cm and 16.6 cm in diameter. For each block, there is a 16 x 16 array of 2 mm x 2 mm x 15 mm lutetium yttrium oxyorthosilicate (LYSO) crystals. In the simulated measurements, the spatial resolution is at the center of the FOV of 1.73 +/- 0.07 mm (radial) and 1.81 +/- 0.08 mm (tangential), but of 4.83 +/- 0.09 mm (radial) and 4.37 +/- 0.07 mm (tangential) while 5 cm off the center. The central point source sensitivity (ACS) is 4.04% (1.50 Mcps/mCi) at an energy window of 350-650 keV. Moreover, the capillary and cylindrical sources are simulated coupled to breast phantoms for the scatter fraction (SF) and Noise Equivalent Count Rate (NECR) test. For a breast phantom with a 350-650 keV energy window, SF may reach the highest 32.95%, while NECR is degraded down to the lowest 255.71 kcps/mCi. Finally, we model a breast phantom embedded with two spheres of different activities. The reconstructed image gives good results despite a bit of difference in image contrast. Further, the image quality will be improved by scatter and random correction. All these test results indicate the feasibility of this PEM system for breast cancer detection.
学科主题	Physics
类目[WOS]	Physics, Nuclear ; Physics, Particles & Fields
收录类别	SCI
WOS记录号	WOS:000274095100029
公开日期	2016-05-03
内容类型	期刊论文
源URL	[http://ir.ihep.ac.cn/handle/311005/226530]
专题	高能物理研究所_多学科研究中心
推荐引用方式 GB/T 7714	Yan Q,Gao J,Dan BC,et al. Preliminary simulation studies on a cylindrical PEM scanner using GATE[J]. CHINESE PHYSICS C,2010,34(1):#REF!.
APA	闫强.,高娟.,单保慈.,魏龙.,Yan, Q.,...&Wei, L.(2010).Preliminary simulation studies on a cylindrical PEM scanner using GATE.CHINESE PHYSICS C,34(1),#REF!.
MLA	闫强,et al."Preliminary simulation studies on a cylindrical PEM scanner using GATE".CHINESE PHYSICS C 34.1(2010):#REF!.