Lanthanide ion-doped GdPO4 nanorods with dual-modal bio-optical and magnetic resonance imaging properties

	Lanthanide ion-doped GdPO4 nanorods with dual-modal bio-optical and magnetic resonance imaging properties
	Ren WL(任文璐); Tian G(田甘); Zhou LJ(周亮君); Ren, WL; Tian, G; Zhou, LJ; Yin, WY; Yan, L; Jin, S; Zu, Y
刊名	NANOSCALE
	2012
卷号	4 期号:12 页码:3754-3760
英文摘要	Here, dual-modal bioprobes for combined optical and magnetic resonance (MR) imaging are reported. Gadolinium orthophosphate (GdPO4) nanorods co-doped with light-emitting lanthanide ions have been successfully prepared through a hydrothermal method. An efficient downconversion luminescence from Ce/Tb or Eu doped GdPO4 nanorods and upconversion luminescence from Yb/Er co-doped GdPO4 nanorods are observed, respectively, which offers the optical modality for the nanoprobes. Notably, we first report the upconversion phenomenon based on the GdPO4 matrix under 980 nm near infrared irradiation. The possibility of using these nanoprobes with downconversion and upconversion luminescent emissions for optical cell imaging is also demonstrated. Furthermore, these Gd3+-containing nanophosphors show good positive signal-enhancement ability when performed under a 4.7 T MR imaging scanner, indicating they have potential as T-1 MR imaging contrast agents. Thus, nanoprobes based on GdPO4 nanophosphors are shown to provide the dual modality of optical and MR imaging.
学科主题	Chemistry; Science & Technology - Other Topics; Materials Science; Physics
收录类别	SCI
WOS记录号	WOS:000304666700027
公开日期	2016-05-03
内容类型	期刊论文
源URL	[http://ir.ihep.ac.cn/handle/311005/224242]
专题	高能物理研究所_多学科研究中心
推荐引用方式 GB/T 7714	Ren WL,Tian G,Zhou LJ,et al. Lanthanide ion-doped GdPO4 nanorods with dual-modal bio-optical and magnetic resonance imaging properties[J]. NANOSCALE,2012,4(12):3754-3760.
APA	任文璐.,田甘.,周亮君.,Ren, WL.,Tian, G.,...&赵宇亮.(2012).Lanthanide ion-doped GdPO4 nanorods with dual-modal bio-optical and magnetic resonance imaging properties.NANOSCALE,4(12),3754-3760.
MLA	任文璐,et al."Lanthanide ion-doped GdPO4 nanorods with dual-modal bio-optical and magnetic resonance imaging properties".NANOSCALE 4.12(2012):3754-3760.